Hong Young-Ho, Kim Chang-Hyun, Che Gil-Sung, Lee Sang-Hoon, Ghang Chang-Gu, Choi Yu-Seok
Department of Neurosurgery, Cerebro-Vascular Center, Bongseng Memorial Hospital, Busan, Korea.
J Korean Neurosurg Soc. 2011 Oct;50(4):327-31. doi: 10.3340/jkns.2011.50.4.327. Epub 2011 Oct 31.
The aim of this study is to investigate the clinical outcomes of surgery and coiling and analyze the predicting factors affecting the clinical outcomes of ruptured posterior inferior cerebellar artery (PICA) aneurysms.
During the last 15 years, 20 consecutive patients with ruptured PICA aneurysms were treated and these patients were included in this study. The Fisher's exact test was used for the statistical significance of Glasgow Outcome Scale (GOS) according to initial Hunt-Hess (H-H) grade, treatment modalities, and the presence of acute hydrocephalus.
Eleven (55%) and nine (45%) patients were treated with surgical clipping and endovascular treatment, respectively. Among 20 patients, thirteen (65.0%) patients had good outcomes (GOS 4 or 5). There was the statistical significance between initial poor H-H grade, the presence of acute hydrocephalus and poor GOS.
In our study, we suggest that initial H-H grade and the presence of acute hydrocephalus may affect the clinical outcome rather than treatment modalities in the ruptured PICA aneurysms.
本研究旨在探讨手术夹闭和血管内栓塞治疗的临床效果,并分析影响破裂性小脑后下动脉(PICA)动脉瘤临床效果的预测因素。
在过去15年中,连续治疗了20例破裂性PICA动脉瘤患者,并将这些患者纳入本研究。采用Fisher精确检验分析格拉斯哥预后量表(GOS)根据初始Hunt-Hess(H-H)分级、治疗方式和急性脑积水的存在情况的统计学意义。
分别有11例(55%)和9例(45%)患者接受了手术夹闭和血管内治疗。20例患者中,13例(65.0%)患者预后良好(GOS 4或5)。初始H-H分级差、存在急性脑积水与GOS差之间存在统计学意义。
在我们的研究中,我们认为初始H-H分级和急性脑积水的存在可能影响破裂性PICA动脉瘤的临床效果,而非治疗方式。