Horowitz M, Kopitnik T, Landreneau F, Krummerman J, Batjer H H, Thomas G, Samson D
Department of Neurological Surgery, University of Texas Southwestern Medical Center at Dallas, 75235-3555, USA.
Neurosurgery. 1998 Nov;43(5):1026-32. doi: 10.1097/00006123-199811000-00012.
Posteroinferior cerebellar artery aneurysms have an incidence of approximately 0.49%. Reports in the literature are sparse concerning outcomes in this patient population. We report our results for 38 consecutive patients who were treated during the last 6.5 years.
All patients (n = 38) with posteroinferior cerebellar artery aneurysms that were surgically treated at Zale-Lipshy University Hospital between January 1990 and May 1997 were retrospectively reviewed. Data were collected and analyzed relating to demographics, condition at presentation, lesion characteristics, associated medical problems, postsurgical complications, and outcome.
Sixty-six percent of the patients (n = 25) experienced neurological sequelae, which included symptomatic vasospasm, hydrocephalus, dysarthria, paresis, diplopia, ataxia, and facial paralysis. Many, however, showed significant improvement during their hospitalization and during the course of the ensuing year. Seventy-four percent of the patients had a Glasgow Outcome Scale score of 1 or 2 at the time of discharge, 91% at 6 months after surgery, and 89% at 1 year after surgery.
This review summarizes the presentations and outcomes of 38 consecutive surgical cases during a 6.5-year period and concludes that posteroinferior cerebellar artery aneurysms are not benign entities. The study does, however, also demonstrate that patients have significant recuperative potential after the treatment of these lesions.
小脑后下动脉动脉瘤的发病率约为0.49%。关于该患者群体治疗结果的文献报道较少。我们报告了过去6.5年中连续治疗的38例患者的结果。
回顾性分析1990年1月至1997年5月在扎勒-利普希大学医院接受手术治疗的所有38例小脑后下动脉动脉瘤患者。收集并分析了有关人口统计学、就诊时状况、病变特征、相关医疗问题、术后并发症及结果的数据。
66%的患者（n = 25）出现神经后遗症，包括有症状的血管痉挛、脑积水、构音障碍、轻瘫、复视、共济失调和面瘫。然而，许多患者在住院期间及随后一年中病情有显著改善。74%的患者出院时格拉斯哥预后量表评分为1或2分，术后6个月时为91%，术后1年时为89%。
本综述总结了6.5年期间38例连续手术病例的临床表现及结果，得出小脑后下动脉动脉瘤并非良性病变的结论。不过，该研究也表明，这些病变治疗后患者有显著的恢复潜力。
