Franke A, Tessmann D, Busch H, Weber J, Pertschy A
Abteilung für viszerale Chirurgie, Bereichs Medicazin, Universität Rostock, DDR.
Z Exp Chir Transplant Kunstliche Organe. 1990;23(1):55-9.
The electrostimulation of the cicatricial healing in the abdominal wall were tested in 119 Wistar rats by means of bipolar rectangularly pulsed current (0.87 Hz, +/- 25 mu A) and direct current (1 mu A). Doubling of the fascia of an abdominal wall hernia was carried out in three groups of rats. In the first group the operational region was stimulated by rectangularly pulsed current, strong proliferated cicatrices were formed with premature production of fibroblasts and collagenous fibres, fast maturation, and high strength. In the second group it was stimulated by direct current, a less exact longitudinal orientation of the collagenous fibres and a slower cicatricial maturation were shown. The third group applied as a control showed a cicatricial distension up to 5 mm. The electrostimulation of the proliferation of connective tissue and cicatricial healing could be pointed out between different tissues (peritoneum and fascia).
采用双极矩形脉冲电流(0.87Hz,±25μA)和直流电(1μA),对119只Wistar大鼠进行腹壁瘢痕愈合的电刺激试验。在三组大鼠中进行腹壁疝筋膜加倍手术。第一组用矩形脉冲电流刺激手术区域,形成了强烈增殖的瘢痕,成纤维细胞和胶原纤维过早产生,成熟快,强度高。第二组用直流电刺激,显示出胶原纤维的纵向排列不太精确,瘢痕成熟较慢。作为对照的第三组显示瘢痕扩张达5毫米。不同组织(腹膜和筋膜)之间可观察到结缔组织增殖和瘢痕愈合的电刺激作用。