Samtsov A V, Shiliaeva L V
Vestn Dermatol Venerol. 1990(6):13-5.
Electron microscopic examination of epithelioid-cell granulomas of two patients with total sarcoidosis and of three ones with isolated sarcoidosis of the skin (sarcoid reactions) has revealed a morphologic polarization of epithelioid cells, manifesting as 4 zones: (1) crimped [correction of chimp] edge zone, (2) zone of vesicles and vacuoles, (3) basal zone, (4) osmiophilic granules zone. The structure of epithelioid cells in sarcoidosis and in sarcoid reactions was found similar, evidencing a high biosynthetic function of the cells.
对两名全身性结节病患者和三名皮肤孤立性结节病患者（结节反应）的上皮样细胞肉芽肿进行电子显微镜检查，发现上皮样细胞存在形态极化，表现为4个区域：（1）卷曲边缘区，（2）囊泡和空泡区，（3）基底区，（4）嗜锇颗粒区。发现结节病和结节反应中上皮样细胞的结构相似，证明这些细胞具有高生物合成功能。
