Abe Yutaka, Mutsuga Motoh, Hirahara Yoshichika, Kawamura Yoko
National Institute of Health Sciences, Tokyo, Japan.
Shokuhin Eiseigaku Zasshi. 2011;52(5):309-13. doi: 10.3358/shokueishi.52.309.
A test method for 6 phthalates, bis(2-ethylhexyl)phthalate, dibutyl phthalate, benzyl butyl phthalate, diisononyl phthalate, diisodecyl phthalate and di-n-octyl phthalate, in polyvinyl chloride (PVC) was developed. GC/MS was used in the SIM mode for the separation and detection of phthalates. For preparation of the test solution, the extraction method with acetone-hexane mixture (3 : 7) and the dissolution method with tetrahydrofuran and ethanol were compared and it was confirmed that each method gave good recoveries. Dilution of the test solution was effective to reduce the influence of PVC. In a collaborative study with nine laboratories, the intra-laboratory variations showed good repeatability, but the measurements at some laboratories deviated widely. It appears that this method is unsuitable for the judgment of acceptability, but it may be suitable for the determination of phthalate content in PVC products.
开发了一种用于测定聚氯乙烯（PVC）中6种邻苯二甲酸酯类物质（邻苯二甲酸二（2-乙基己基）酯、邻苯二甲酸二丁酯、邻苯二甲酸苄基丁酯、邻苯二甲酸二异壬酯、邻苯二甲酸二异癸酯和邻苯二甲酸二正辛酯）的测试方法。采用气相色谱/质谱联用仪在选择离子监测（SIM）模式下对邻苯二甲酸酯类进行分离和检测。对于测试溶液的制备，比较了丙酮-己烷混合物（3:7）萃取法和四氢呋喃与乙醇溶解法，结果证实每种方法的回收率都很好。稀释测试溶液可有效降低PVC的影响。在与9个实验室的协同研究中，实验室内的变化显示出良好的重复性，但一些实验室的测量结果偏差较大。看来该方法不适用于可接受性判断，但可能适用于PVC产品中邻苯二甲酸酯含量的测定。
