Risse M, Weiler G
Institut für Rechtsmedizin, Universitätsklinikum Essen, Bundesrepublik Deutschland.
Z Rechtsmed. 1990;103(7):507-12. doi: 10.1007/BF01254402.
Age (eight days to 12 months) and degree of colloid depletion or colloid content of the follicles (normal, partially depleted, depleted) were correlated on the basis of 176 thyroid investigations in cases of sudden infant death syndrome (SIDS). In the 176 SIDS cases, a resting thyroid gland with normal colloid content could only be found in 14%, whereas partially depleted follicles were found in 35% and depleted follicles in 51%. 60% of all cases showed a large degree of epithelial desquamation up to collapse of all follicles. A marked capillary hyperemia was found in 48%. 80% of the cases showed a normal colloid content in the first month of life, and colloidfree follicles should not be detected in any case. An increased incidence of thyroid activation was obtained in the total number of cases only from the second month of life. The histomorphological appearance of the thyroid gland thus corresponds to that of healthy infants only in the first month of life. The question as to why there is an evidently raised thyroid activity in the subsequent months of life in SIDS cases is discussed.
在176例婴儿猝死综合征（SIDS）病例的甲状腺检查基础上，对年龄（8天至12个月）与滤泡胶体消耗程度或胶体含量（正常、部分消耗、消耗）进行了相关性分析。在这176例SIDS病例中，仅14%的病例甲状腺处于静止状态且胶体含量正常，35%的病例滤泡部分消耗，51%的病例滤泡消耗。所有病例中有60%出现大量上皮脱屑，直至所有滤泡塌陷。48%的病例发现明显的毛细血管充血。80%的病例在出生后第一个月胶体含量正常，且在任何情况下都不应检测到无胶体滤泡。仅从出生后第二个月起，病例总数中甲状腺激活的发生率增加。因此，甲状腺的组织形态学表现仅在出生后第一个月与健康婴儿的表现相符。文中讨论了SIDS病例在出生后后续几个月甲状腺活性明显升高的原因。
