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抗焦虑药可减轻良性阵发性位置性眩晕患者成功进行耳石复位手法治疗后的残余头晕症状。

Anxiolytics reduce residual dizziness after successful canalith repositioning maneuvers in benign paroxysmal positional vertigo.

作者信息

Jung Hahn Jin, Koo Ja-Won, Kim Chong Sun, Kim Ji Soo, Song Jae-Jin

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.

出版信息

Acta Otolaryngol. 2012 Mar;132(3):277-84. doi: 10.3109/00016489.2011.637179. Epub 2011 Dec 27.

Abstract

CONCLUSIONS

This study suggests that adjuvant anti-anxiety medication may be helpful for patients with benign paroxysmal positional vertigo (BPPV) even after a successful canalith repositioning procedure (CRP).

OBJECTIVE

Although the CRP is an effective treatment for BPPV, many patients suffer from persistent dizziness despite successful CRPs. The aim of this study was to evaluate the effect of adjuvant anxiolytic medication on residual dizziness after successful CRP.

METHODS

Between January 2011 and March 2011, 73 patients were diagnosed with BPPV and they underwent successful treatment with CRPs. The patients were randomly assigned to either the medication group or the control group. The patients in the medication group were prescribed low dose etizolam for 2 weeks whereas the patients in the control group were not prescribed any medication. All patients were scheduled to return 2 weeks after evaluation of subjective visual vertical. Subjective symptoms before and after CRP were measured using the Dizziness Handicap Inventory (DHI) and the Activities-specific Balance Confidence (ABC) scale.

RESULTS

Both groups demonstrated a significant improvement in DHI scores. However, the medication group showed significantly greater decrease in the functional (p = 0.018) and emotional (p = 0.030) subscale scores, as well as in the total DHI (p = 0.038) score.

摘要

结论

本研究表明,辅助抗焦虑药物治疗对于良性阵发性位置性眩晕(BPPV)患者可能有益,即便在成功进行耳石复位治疗(CRP)之后。

目的

虽然CRP是治疗BPPV的有效方法,但许多患者在CRP成功后仍有持续性头晕。本研究旨在评估辅助抗焦虑药物对CRP成功后残余头晕的影响。

方法

2011年1月至2011年3月期间,73例被诊断为BPPV的患者接受了CRP成功治疗。患者被随机分为药物治疗组或对照组。药物治疗组患者服用低剂量艾司唑仑2周,而对照组患者未服用任何药物。所有患者在主观视觉垂直评估后2周复诊。使用头晕残障量表(DHI)和特定活动平衡信心(ABC)量表测量CRP前后的主观症状。

结果

两组患者的DHI评分均有显著改善。然而,药物治疗组在功能(p = 0.018)和情感(p = 0.030)分量表评分以及DHI总分(p = 0.038)方面的下降更为显著。

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