Park Jonas J-H, Luecke Kerstin, Luedeke Inger, Emmerling Oliver, Westhofen Martin
Department of Otolaryngology and Head and Neck Surgery, University Hospital Aachen, RWTH Aachen University, Germany.
Acta Otolaryngol. 2012 Mar;132(3):266-70. doi: 10.3109/00016489.2011.636378. Epub 2011 Dec 27.
Repetitive portable tympanometry is a feasible method to examine long-term middle ear pressure profile. This method might be suitable for detecting patients with Meniere's disease whose middle ear pressure shows intermittently pathological values.
Contradictory study results regarding middle ear pressure in patients with Meniere's disease might be due to solitary tympanometric measurements. Pathological pressure conditions in patients with pressure regulation disorders might be missed by a single examination. The aim of the study was to examine the pressure profile of patients with Meniere's disease by long-term measurements.
Patients with Meniere's disease (n = 33), patients with sudden hearing loss (n = 20), and healthy subjects (n = 30) were examined. Patients carried out long-term middle ear pressure measurements with the portable tympanometer Otoflex 100. Examinations were carried out during daily activities at defined time intervals.
Significant negative middle ear pressure were seen in patients with Meniere's disease compared with patients with sudden hearing loss and healthy subjects (p < 0.01). Average middle ear pressure in patients with Meniere's disease was -43 daPa, in patients with sudden hearing loss it was 2 daPa, and in healthy subjects it was 4 daPa. Patients with Meniere's disease showed a large variability of pressure values ranging from strongly pathological to normal values during long-term measurements.
重复性便携式鼓室导抗测量法是检测中耳压力长期变化情况的一种可行方法。该方法可能适用于检测中耳压力间歇性出现病理值的梅尼埃病患者。
关于梅尼埃病患者中耳压力的研究结果相互矛盾，可能是由于单次鼓室导抗测量所致。压力调节障碍患者的病理性压力状况可能会被单次检查遗漏。本研究的目的是通过长期测量来检测梅尼埃病患者的压力变化情况。
对梅尼埃病患者（n = 33）、突发性听力损失患者（n = 20）和健康受试者（n = 30）进行检查。患者使用便携式鼓室导抗仪Otoflex 100进行中耳压力长期测量。在日常活动期间按规定时间间隔进行检查。
与突发性听力损失患者和健康受试者相比，梅尼埃病患者出现显著的中耳负压（p < 0.01）。梅尼埃病患者的平均中耳压力为-43 daPa，突发性听力损失患者为2 daPa，健康受试者为4 daPa。在长期测量中，梅尼埃病患者的压力值变化很大，范围从严重病理性到正常。
