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[刺激“奖赏区”对家兔束旁复合体诱发电位影响的个体发生学特征]

[The ontogenetic characteristics of the effect of stimulating the "reward zones" on the evoked potential in the parafascicular complex of the rabbit].

作者信息

Butkevich I P, Kassil' V G

出版信息

Zh Evol Biokhim Fiziol. 1990 May-Jun;26(3):390-7.

PMID:2220209
Abstract

In experiments on 24 anaesthetized 30-40-days rabbits, studies have been made of the effect of stimulation of the "reward zones" on the evoked potentials in the parafascicular complex in response to nociceptive stimulation of the hindlimb. It was shown that the effect of depression depends on the strength and duration of stimulation, being more evident in animals with a strong reaction to self-stimulation. A comparison was made of analgetic effects produced by stimulation of the reward zones in various brain structures (the anterior, median and posterior lateral hypothalamus, the capsula interna, subthalamic region, etc.). Original description is presented of ontogenetic peculiarities of the recovery period for the evoked potentials after cessation of stimulation. The data obtained are discussed in relation to functional properties of nonspecific thalamic system of rabbits at the given stage of their development.

摘要

在对24只30 - 40日龄麻醉兔进行的实验中,研究了刺激“奖赏区”对后肢伤害性刺激引起的束旁复合体诱发电位的影响。结果表明,抑制作用的效果取决于刺激的强度和持续时间,在对自我刺激反应强烈的动物中更为明显。对刺激不同脑结构(下丘脑前区、中区和后外侧区、内囊、丘脑底区等)的奖赏区所产生的镇痛效果进行了比较。给出了刺激停止后诱发电位恢复期的个体发育特点的原始描述。结合家兔在其发育的给定阶段非特异性丘脑系统的功能特性对所得数据进行了讨论。

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