Marantidi A N, Vul'fovich Iu V, Gamova N A, Krylova R I
Zh Mikrobiol Epidemiol Immunobiol. 1990 Jun(6):13-8.
The possibility of modeling chronic infection on monkeys by the injection of the culture of U. urealyticum, serotype VIII, was shown. The infection of monkeys with these microorganisms introduced in a single intraperitoneal injection resulted in the generalization of the process, which was manifested by the persistence and reproduction of the infective agent in the organs and blood of the animals for as long as 6 months (the term of observation). Lymphoid hyperplasia in the organs of immunogenesis and transitory immunomorphological reaction in the tissues of some organs of the urogenital system were noted. The localization of infective agents in some endocrine glands was not accompanied by disturbances in their function.
已证实通过注射解脲脲原体VIII型培养物在猴子身上模拟慢性感染的可能性。单次腹腔注射这些微生物使猴子受到感染,导致感染过程扩散,表现为感染因子在动物器官和血液中持续存在并繁殖长达6个月(观察期)。观察到免疫发生器官中的淋巴样增生以及泌尿生殖系统某些器官组织中的短暂免疫形态学反应。感染因子在一些内分泌腺中的定位并未伴随其功能紊乱。