Attempts to produce gynaecological disease in grivet monkeys with Ureaplasma urealyticum.

Attempts were made to infect grivet monkeys with Ureaplasma urealyticum, including strains freshly isolated from patients with infection of the genito-urinary tact, laboratory reference strains and simian strains. The organisms were inoculated directly into the uterine tubes exposed at laparotomy, or through the cervical canal into the uterine cavity before endometrial curettage; but only colonisation, of up to 5 months' duration, was achieved, without evidence of inflammation in the genital tract or elsewhere, and without an antibody response.