Imada Shinya, Ohue Masayuki, Noura Shingo, Shingai Tatsushi, Motoori Masaaki, Kishi Kentarou, Miyashiro Isao, Nishiyama Kinji, Yano Masahiko, Ishikawa Osamu
Dept. of Gastrointestinal Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases.
Gan To Kagaku Ryoho. 2011 Nov;38(12):2119-21.
We report a case with perianal squamous cell carcinoma, which showed a complete response more than five years after chemoradiotherapy. A 69-year-old-man was introduced to our hospital for the diagnosis of squamous cell carcinoma [T3 (8.0 × 8.0 cm) N0M0, Stage II]. The patient was treated by chemoradiotherapy, which consisted of 5-FU 750 mg/m²/ day (continuous intravenously) on days 1-5 and 29-33, and mitomycin C 10 mg/m² on days 1 and 29 and radiation at 2 Gy/day for 5 days per week (total dose 60 Gy). The patient tolerated this treatment with no severe adverse effects. Tumor disappeared completely 1 month after this treatment with no adjuvant therapy. The patient has been alive with no sign of recurrence for 6 years.
我们报告一例肛周鳞状细胞癌患者，该患者在放化疗后五年多出现完全缓解。一名69岁男性因鳞状细胞癌诊断[T3（8.0×8.0 cm）N0M0，II期]被转诊至我院。患者接受了放化疗，具体方案为第1 - 5天和第29 - 33天静脉持续输注5-氟尿嘧啶750 mg/m²/天，第1天和第29天静脉注射丝裂霉素C 10 mg/m²，每周5天，每天放疗2 Gy（总剂量60 Gy）。患者耐受该治疗，未出现严重不良反应。此次治疗后1个月，肿瘤完全消失，未进行辅助治疗。患者已存活6年，无复发迹象。
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