Onozawa Hisashi, Ishii Yoshimasa, Yamada Mutsuo, Okada Ryo, Takenoshita Seiichi
Dept. of Surgery, Ota Nishinouchi Hospital.
Gan To Kagaku Ryoho. 2011 May;38(5):823-6.
A 39-year-old man with psoriasis vulgaris who complained of severe anemia was examined and diagnosed with advanced gastric cancer (UM, Type 3, cT3 cN2 cH0 cP0 cM0, cStage III B). He was treated with S-1/CDDP as neoadjuvant chemotherapy. S-1 (120mg/day) was administered orally for 14 days, followed by 7 drug-free days as a course, and CDDP (100mg/ body) was administered by intravenous drip on day 8. After the third course, a significant tumor reduction was obtained. Total gastrectomy and lymph node dissection (D2) were performed. The histological diagnosis revealed a complete disappearance of cancer cells in the stomach and all of the lymph nodes. He has been doing well without any recurrence for 9 months since the start of treatment.
一名39岁寻常型银屑病男性患者,因严重贫血就诊,经检查诊断为进展期胃癌(UM,3型,cT3 cN2 cH0 cP0 cM0,cⅢB期)。给予S-1/顺铂作为新辅助化疗。S-1(120mg/天)口服14天,随后停药7天为一个疗程,顺铂(100mg/体)在第8天静脉滴注。第三个疗程后,肿瘤明显缩小。行全胃切除术及淋巴结清扫术(D2)。组织学诊断显示胃及所有淋巴结癌细胞完全消失。自治疗开始以来,他情况良好,9个月未复发。