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1例不可切除的晚期胃癌采用S-1/顺铂化疗后行胃切除术并获得组织学完全缓解

[A case of S-1/CDDP chemotherapy for inoperable advanced gastric cancer which led to gastrectomy with histological complete response].

作者信息

Kobayashi Kenji, Tanizaki Keiko, Aoki Taro, Takachi Kou, Nishioka Kiyonori, Matsumoto Takashi, Komori Takamichi, Chono Teruhiro, Kato Aya, Hyuga Satoshi, Watanabe Risa, Uemura Yoshio

机构信息

Dept. of Surgery, Kinki Central Hospital.

出版信息

Gan To Kagaku Ryoho. 2011 Nov;38(12):1951-3.

PMID:22202249
Abstract

As the treatment for inoperable advanced gastric cancer, S-1/CDDP combination therapy (SP chemotherapy) has become a standard treatment. In our hospital, a second course of chemotherapy was performed on an outpatient basis in order to improve a traditional QOL. In this case, it showed remarkable effects in 15 months after starting chemotherapy. Then gastrectomy was performed. Histological findings of the resected specimens confirmed pCR in all tumors. We report on progress of this case and explain about the ingenuity of SP chemotherapy.

摘要

作为不可切除的晚期胃癌的治疗方法,S-1/顺铂联合疗法(SP化疗)已成为标准治疗方案。在我院,为了改善传统的生活质量,第二疗程化疗在门诊进行。在这种情况下,化疗开始15个月后显示出显著效果。随后进行了胃切除术。切除标本的组织学检查结果证实所有肿瘤均达到病理完全缓解(pCR)。我们报告该病例的进展情况,并解释SP化疗的精妙之处。

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