南非纳马夸岩鼠（Rodentia：Muridae）的巴尔通体菌。
Bartonellae of the Namaqua rock mouse, Micaelamys namaquensis (Rodentia: Muridae) from South Africa.
机构信息
Mammal Research Institute (MRI), Department of Zoology and Entomology, University of Pretoria, Private Bag 20, Hatfield, 0028 South Africa.
出版信息
Vet Microbiol. 2012 May 25;157(1-2):132-6. doi: 10.1016/j.vetmic.2011.12.006. Epub 2011 Dec 11.
The aim of this study was to determine Bartonella prevalence and diversity in Namaqua rock mice, Micaelamys namaquensis, a species endemic to South Africa, which can attain pest status. A total of 100 heart samples collected monthly from March to December were screened for Bartonella genome presence using three primer sets targeting the citrate synthase (gltA) gene, the NADH dehydrogenase gamma subunit (nuoG) gene and the RNA polymerase β-subunit-encoding gene (rpoB). An overall prevalence of 44% was obtained, with no statistically significant differences or correlations between infection rates and rodent sex, month of capture or season of capture. Phylogenetic analysis of 34 unambiguous gltA sequences revealed the presence of three discrete Bartonella lineages in M. namaquensis, one of which corresponds to Bartonella elizabethae, a species with known zoonotic potential.
本研究旨在确定 Namaqua 岩鼠（Micaelamys namaquensis）中巴尔通体的流行率和多样性。Namaqua 岩鼠是南非特有的一种可能成为害虫的物种。使用针对柠檬酸合酶（gltA）基因、NADH 脱氢酶γ亚基（nuoG）基因和 RNA 聚合酶β亚基编码基因（rpoB）的三个引物组，对 3 月至 12 月每月采集的 100 份心脏样本进行了巴尔通体基因组存在的筛查。总体流行率为 44%，感染率与啮齿动物的性别、捕获月份或捕获季节之间无统计学显著差异或相关性。34 条明确 gltA 序列的系统发育分析显示，M. namaquensis 中存在三种不同的巴尔通体谱系，其中一种与具有已知人畜共患潜力的 Bartonella elizabethae 相对应。
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