Yamagami J, Shirato S, Araie M
Department of Ophthalmology, School of Medicine University of Tokyo, Japan.
Nippon Ganka Gakkai Zasshi. 1990 May;94(5):514-8.
To study the effect of the intraocular pressure (IOP) on the visual field (VF) damage in low tension glaucoma (LTG), we compared the IOP and the VF damage in both eyes of 46 LTG patients. As an index of the VF damage, we used the mean deviation (MD) value calculated by the Humphry (30-2) STATPAC program, and for the IOP data, the mean of 24 hour IOP measurements (diurnal IOP) and the mean of the IOPs measured at each visit to our outpatient clinics (follow-up IOP). In 13 cases, the diurnal and the follow-up IOPs were 0.3 mmHg higher or more in the more damaged eye than those in the less damaged eye, and in 7 cases they were 0.3 mmHg higher or more in the less damaged eye than those in the more damaged eye. Between these two groups, no significant difference was seen in the value of MD, but the diurnal IOP and the follow-up IOP was significantly higher in the former than in the latter group. By discrimination analysis, the two groups were distinguished at the diurnal IOP of 14.1 mmHg (hit rate 77.6%) and the follow-up IOP of 15.0 mmHg (74.2%). An analysis using the whole 46 LTG cases yielded the following results: when the diurnal or follow-up IOP of the more damaged eye was higher than the above determined level, the IOP in the more damaged eye was significantly higher than that in the contralateral less damaged eye.(ABSTRACT TRUNCATED AT 250 WORDS)
为研究眼压（IOP）对低眼压性青光眼（LTG）视野（VF）损害的影响，我们比较了46例LTG患者双眼的眼压和视野损害情况。作为视野损害的指标，我们使用了由Humphry（30 - 2）STATPAC程序计算得出的平均偏差（MD）值，对于眼压数据，采用24小时眼压测量的平均值（昼夜眼压）以及每次门诊就诊时测量的眼压平均值（随访眼压）。在13例患者中，损害较重眼的昼夜眼压和随访眼压比损害较轻眼高0.3 mmHg或更多，在7例患者中，损害较轻眼的昼夜眼压和随访眼压比损害较重眼高0.3 mmHg或更多。在这两组之间，MD值未见显著差异，但前一组的昼夜眼压和随访眼压显著高于后一组。通过判别分析，两组在昼夜眼压为14.1 mmHg（命中率77.6%）和随访眼压为15.0 mmHg（74.2%）时得以区分。对全部46例LTG病例进行分析得出以下结果：当损害较重眼的昼夜眼压或随访眼压高于上述确定水平时，损害较重眼的眼压显著高于对侧损害较轻眼。（摘要截断于250字）
