Kakisu Y, Adachi-Usami E, Fujimoto N
Dept. of Ophthalmol., School of Med., Chiba Univ., Japan.
Nippon Ganka Gakkai Zasshi. 1990 Jul;94(7):673-8.
Magnetic resonance imaging (MRI) was performed in 14 patients with optic neuritis. Three patients suffered from multiple sclerosis but the etiologies of the remaining 11 cases could not be identified. They were bilateral in 6, and unilateral in 8. The MR images were compared with the symptomatic lesions of optic neuritis and pattern reversal VECP. The STIR mode (short time inversion recovery), was employed for the MRI in the orbit and T2-weighted mode in the brain. In 11 eyes with hyperemia of the optic disc, 7 eyes showed a high signal in the optic nerve with the MRI, and 9 eyes showed an abnormal pattern VECP. Seven eyes with normal disc and two eyes with a pale disc showed a high signal in the optic nerve with MRI, those 9 eyes had abnormal pattern VECP. The high signal in the optic nerve was not related to visual acuity or visual field abnormalities of patients. However, the degree of the high signal of the optic nerve lesion in MRI was associated with the clinical course and prognosis of the optic neuritis. The degree of the high signal of the optic nerve lesion decreased with the recovery of visual acuity in optic neuritis.
对14例视神经炎患者进行了磁共振成像（MRI）检查。3例患者患有多发性硬化症，但其余11例的病因无法确定。其中6例为双侧病变，8例为单侧病变。将MR图像与视神经炎的症状性病变及图形翻转视觉诱发电位（VECP）进行了比较。眼眶MRI采用短时间反转恢复（STIR）模式，脑部采用T2加权模式。在11只视盘充血的眼睛中，7只眼睛在MRI上显示视神经高信号，9只眼睛显示图形VECP异常。7只视盘正常的眼睛和2只视盘苍白的眼睛在MRI上显示视神经高信号，这9只眼睛图形VECP异常。视神经高信号与患者的视力或视野异常无关。然而，MRI上视神经病变的高信号程度与视神经炎的临床病程及预后相关。视神经炎患者视力恢复时，视神经病变的高信号程度降低。
