[急性视神经炎：临床及MRI预后因素。五十例患者的研究]

[Acute optic neuritis: clinical and MRI prognostic factors. Study of fifty patients].

作者信息

Deschamps R, Gout O, Fontaine B, Rigolet M H, Cabanis E A, Lyon-Caen O, Tourbah A

机构信息

Fédération de Neurologie, Groupe Hospitalier Pitié-Salpêtrière.

出版信息

Rev Neurol (Paris). 2002 Apr;158(4):446-52.

PMID:11984487

Abstract

The objective of this study was to evaluate the risk of visual outcome after acute optic neuritis (ON) in relation to clinical and MRI findings. Fifty cases of acute ON within one month were retrospectively studied. MRI with Short Tau Inversion Recovery (STIR) sequence of the optic nerve were obtained with a median time onset of 9 days after ON. Mean age of patients was 32.8 years, mean initial visual acuity was 3/10 and orbital pain was present in 86 percent100 of patients. The STIR sequence revealed lesion in 88 percent 100 of acutely symptomatic optic nerves. An initial low visual acuity (less than 2/10), the absence of orbital pain and involvement of the intracanalicular portion of the optic nerve on STIR sequence were statistically correlated with a poorer visual outcome (respectively p=0.0041, p=0.035 and p=0.011).

摘要

本研究的目的是评估急性视神经炎（ON）后视力预后的风险与临床及MRI表现的关系。对50例在1个月内发生急性ON的患者进行了回顾性研究。采用视神经短tau反转恢复（STIR）序列MRI检查，ON发病后中位时间为9天。患者平均年龄为32.8岁，平均初始视力为3/10，86%的患者存在眼眶疼痛。STIR序列显示88%的急性症状性视神经有病变。初始视力低（低于2/10）、无眼眶疼痛以及STIR序列显示视神经管内段受累与较差的视力预后在统计学上相关（分别为p=0.0041、p=0.035和p=0.011）。