Kakisu Y, Adachi-Usami E, Fujimoto N
Department of Ophthalmology, School of Medicine, Chiba University, Japan.
J Clin Neuroophthalmol. 1991 Sep;11(3):205-12.
We studied the extent of optic nerve lesion with magnetic resonance imaging (MRI) in 24 patients with optic neuritis and compared it with visually evoked cortical potentials (VECP). Patients were divided into acute and chronic stage groups according to the duration of the disease from its onset. The short TI inversion recovery (STIR) mode of the MRI was selected for study. In the acute stage group, abnormally high signals of optic nerve on MRI were demonstrated in 11 of 12 eyes, and the amplitude and peak latency of pattern VECP were unrelated to the extent of the optic nerve lesion visualized by MRI. Conversely, in the chronic stage group, the abnormal MRI findings were exhibited in 19 of 23 eyes, and the relationship between the measurements was statistically significant. This difference in the optic nerve lesion observed by MRI between the acute stage and the chronic stage of optic neuritis may indicate pathophysiologic differences in their origins.
我们用磁共振成像（MRI）研究了24例视神经炎患者的视神经损伤程度，并将其与视觉诱发电位（VECP）进行了比较。根据疾病自发病起的病程，将患者分为急性期组和慢性期组。选择MRI的短TI反转恢复（STIR）模式进行研究。在急性期组中，12只眼中有11只眼在MRI上显示视神经信号异常增高，图形VECP的波幅和峰潜伏期与MRI显示的视神经损伤程度无关。相反，在慢性期组中，23只眼中有19只眼出现MRI异常表现，且各项测量指标之间的关系具有统计学意义。视神经炎急性期和慢性期MRI观察到的视神经损伤差异可能表明其发病机制存在病理生理差异。
