Bergstrom Kendra Gail
J Drugs Dermatol. 2012 Jan;11(1):126-8.
Atopic dermatitis is increasing in prevalence throughout the developed world, in parallel with asthma and hay fever. The reasons for the increase remain unclear. As a practical question, it is valuable to understand which interventions might decrease risk for childhood atopic disease. Prospective studies among infants and children are challenging to design and to execute. Fortunately, several large studies from Europe and the United States are better characterizing whether behavioral interventions such as breastfeeding, delayed introduction of solid foods, hydrolyzed protein infant formulas, or pets in the home might be protective or impart increased risk of developing atopic dermatitis. As this body of literature grows, physicians will be able to recommend behavioral interventions that can prevent atopic dermatitis in individuals and ideally decrease prevalence over the population.
在整个发达国家，特应性皮炎的患病率正在上升，与哮喘和花粉热的情况相似。患病率上升的原因尚不清楚。从实际角度来看，了解哪些干预措施可能降低儿童患特应性疾病的风险很有价值。对婴儿和儿童进行前瞻性研究在设计和实施方面都具有挑战性。幸运的是，欧洲和美国的几项大型研究正在更好地描述诸如母乳喂养、延迟引入固体食物、水解蛋白婴儿配方奶粉或家中饲养宠物等行为干预措施是否可能具有保护作用，或者是否会增加患特应性皮炎的风险。随着这方面文献的不断增加，医生将能够推荐一些行为干预措施，这些措施可以预防个体患特应性皮炎，并理想地降低整个人群的患病率。
