Department of Psychiatry and Psychotherapy, University of Leipzig, Leipzig, Germany.
World J Biol Psychiatry. 2013 May;14(4):248-57. doi: 10.3109/15622975.2011.623717. Epub 2011 Dec 29.
Although Kraepelin and his oeuvre have been in scientific focus over the past decades, main aspects have still been neglected. Thus the exact circumstances under which and on what topic Kraepelin wrote his habilitation thesis and qualified as university lecturer (in Germany the prerequisite to be appointed as professor) are still widely unknown.
This study reconstructs his habilitation at the Medical Faculty of Leipzig University in 1882.
The study reveals the difficulties he had to habilitate on a topic from Wilhelm Wundt's experimental psychology and the opposition he faced from Paul Flechsig. Yet Kraepelin succeeded, mainly due to a positive review by neurologist Wilhelm Erb on his study "On the Influence of Acute Diseases on the Development of Mental Illnesses" (1881/82).
This work must be regarded as his actual habilitation thesis. It provides an update of organic psychiatric disorders following acute inflammatory diseases and a meta-analysis on the basis of raw data. In addition it discusses possibilities to categorize and understand the pathophysiological mechanism of these disorders and to classify them into those appearing when the fever rises and those occurring when it falls, which has a high impact from a very modern psychoimmunological viewpoint.
尽管过去几十年来，克雷丕林及其著作一直是科学研究的焦点，但仍有一些主要方面被忽视了。因此，克雷丕林在什么情况下、针对什么主题撰写了他的资格论文并获得大学讲师资格（在德国，这是被任命为教授的前提条件），这些情况仍然知之甚少。
本研究重建了他于 1882 年在莱比锡大学医学系的资格认证。
该研究揭示了他在威廉·冯特的实验心理学主题上进行资格认证所面临的困难，以及他所面临的来自保罗·弗莱希格的反对。然而，克雷丕林成功了，主要是因为神经病学家威廉·埃布对他的研究“急性疾病对精神疾病发展的影响”（1881/82 年）的积极评价。
这项工作必须被视为他的实际资格论文。它提供了急性炎症性疾病后对器质性精神障碍的更新，并基于原始数据进行了荟萃分析。此外，它还讨论了对这些障碍的病理生理机制进行分类和理解的可能性，并将它们分为发热时出现的障碍和退热时出现的障碍，从非常现代的心理免疫学观点来看，这具有很高的影响。
