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严重大面积烧伤的流行病学与预后分析:中国某烧伤中心103例患者的12年总结

Epidemiology and outcome analysis of severe extensive burns: a 12-year summary of 103 cases in a burn center in China.

作者信息

Xie Bing, Xiao Shi-Chu, Peng Xu-Dong, Zhu Shi-Hui, Lv Kai-Yang, Li Heng-Yu, Xia Zhao-Fan

机构信息

Department of Burn Surgery, Changhai Hospital, The Second Military Medical University, Shanghai, People's Republic of China.

出版信息

J Burn Care Res. 2012 May-Jun;33(3):e127-32. doi: 10.1097/BCR.0b013e3182335a5d.

Abstract

The purpose of this article is to improve the treatment of severe extensive burns (SEB) patients by summarizing treatment experience in recent 12 years in China and analyzing the follow-up quality of life (QOL) in these patients. Clinical data and rescue measures of 103 SEB patients (≥70% TBSA) admitted in a burn center in Shanghai between 1997 and 2009 were reviewed, and QOL and hand function of those who survived more than 2 years were assessed by Brief Version of Burn Specific Health scale-B and Michigan Hand Outcome Questionnaire. Of these, 76.7% were caused by flames and 15.5% caused by scald. The median burn area was 87.5% (interquartile range, 77.0-95.0%) TBSA, of which third-degree burns accounted for 56.5% (interquartile range, 25.8-80.0%) TBSA; 71.8% were complicated by inhalation injury. The occurrence of in-hospital complications was 75.7%, with the respiratory system complications predominating (49.5%). The fatality rate was 28.2%, mainly due to sepsis and multiple organ dysfunction syndrome. Work, body image, and heat sensitivity got the lowest Brief Version of Burn Specific Health scale-B scores in all nine domains, and Michigan Hand Outcome Questionnaire scores were also relatively poor. Flame burns remain to be the main cause of SEB in China in recent 12 years. Treatment is still challenged because of the depth and extensive burn area and high occurrence of multiple system complications. How to ameliorate QOL of SEB patients, intensify the functional rehabilitation, and improve their physical appearance in particular remain to be a crux.

摘要

本文旨在通过总结我国近12年严重大面积烧伤(SEB)患者的治疗经验并分析其随访生活质量(QOL),以改善对该类患者的治疗。回顾了1997年至2009年上海某烧伤中心收治的103例SEB患者(烧伤总面积≥70%)的临床资料及救治措施,并采用烧伤特异性健康量表简版-B(Brief Version of Burn Specific Health scale-B)和密歇根手功能结果问卷对存活超过2年的患者的生活质量和手功能进行评估。其中,76.7%由火焰烧伤引起,15.5%由烫伤引起。烧伤面积中位数为87.5%(四分位间距,77.0 - 95.0%)TBSA,其中三度烧伤占56.5%(四分位间距,25.8 - 80.0%)TBSA;71.8%合并吸入性损伤。住院并发症发生率为75.7%,以呼吸系统并发症为主(49.5%)。病死率为28.2%,主要原因是脓毒症和多器官功能障碍综合征。在所有九个领域中,工作、身体形象和热敏感性在烧伤特异性健康量表简版-B中得分最低,密歇根手功能结果问卷得分也相对较差。火焰烧伤仍是我国近12年SEB的主要原因。由于烧伤深度和面积大以及多系统并发症发生率高,治疗仍面临挑战。如何改善SEB患者的生活质量、加强功能康复,尤其是改善其外貌仍是关键所在。

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