Dou Z, Zhang G A
Department of Burns, Beijing Jishuitan Hospital, Beijing 100035, China.
Zhonghua Shao Shang Za Zhi. 2021 Jul 20;37(7):654-660. doi: 10.3760/cma.j.cn501120-20200306-00129.
To study the epidemiological characteristics of inhalation injury in burn patients in China. The systematic review method was performed. -, and were searched with the Chinese search terms of ", , ", and and were searched with the search terms of "burns, inhalation injury" to retrieve the collected retrospective studies on the epidemiological characteristics of inhalation injury in burn patients in China from the establishment of each database to January 2019. Data were extracted from the included articles, including the first author, study institution, study period, study subjects, number of burn patients, incidence of inhalation injury, and gender, age, causes of injury, mortality, and causes of death in patients with inhalation injury. A total of 24 articles were included in this study with the first authors being from multiple research institutions across the country. The articles reported single or multi-center epidemiological studies with statistics on the incidence of inhalation injury in burn patients or severe burn patients admitted to key burn treatment institutions in many provinces/cities in China from 1958 to 2016. The number of burn patients included was 103-64 320 cases in the studies, and the incidence of inhalation injury in hospitalized burn patients ranged from 4.89% to 11.28%, with no obvious trend. The incidence of inhalation injury in severe burn patients was still high, from 19.09% to 32.38% as most articles reported. The number of men with inhalation injury was larger than that of women, with a male-to-female ratio of 1.61 ∶1.00-4.95 ∶1.00; young and middle-aged people were the high-risk population, and flame burn was the main cause of injury. The mortality of patients with inhalation injury was 5.17%-58.67%, of which the mortality was 5.17%-24.75% since 2000, in accordance with reports from hospitals in various regions that the mortality in the later period decreased significantly compared with the previous period. The causes of death in patients with inhalation injury included upper respiratory tract obstruction, sepsis, respiratory failure, and severe pulmonary infection. From 1958 to 2016, there is no obvious trend in the incidence of inhalation injury among burn patients in China; the incidence of inhalation injury is high in young and middle-aged males, and the main cause of inhalation injury is flame burn. The mortality of inhalation injury generally decreased since 2000 compared with the previous period.
研究我国烧伤患者吸入性损伤的流行病学特征。采用系统评价方法。以中文检索词“烧伤、吸入性损伤、发病率、死亡率、危险因素”检索相关数据库,以英文检索词“burns, inhalation injury”检索相关数据库,检索各数据库建库至2019年1月关于我国烧伤患者吸入性损伤流行病学特征的回顾性研究。从纳入的文章中提取数据,包括第一作者、研究机构、研究时间段、研究对象、烧伤患者数量、吸入性损伤发病率,以及吸入性损伤患者的性别、年龄、致伤原因、死亡率和死亡原因。本研究共纳入24篇文章,第一作者来自全国多个研究机构。这些文章报道了单中心或多中心的流行病学研究,统计了1958年至2016年我国多个省市重点烧伤治疗机构收治的烧伤患者或重度烧伤患者吸入性损伤的发病率。各研究中纳入的烧伤患者数量为103 - 64320例,住院烧伤患者吸入性损伤发病率为4.89%至11.28%,无明显变化趋势。重度烧伤患者吸入性损伤发病率仍较高,多数文章报道为19.09%至32.38%。吸入性损伤男性患者数量多于女性,男女比例为1.61∶1.00至4.95∶1.00;中青年为高危人群,火焰烧伤是主要致伤原因。吸入性损伤患者死亡率为5.17%至58.67%,其中2000年以来死亡率为5.17%至24.75%,各地医院报告显示后期死亡率较前期显著下降。吸入性损伤患者死亡原因包括上呼吸道梗阻、脓毒症、呼吸衰竭和严重肺部感染。1958年至2016年,我国烧伤患者吸入性损伤发病率无明显变化趋势;中青年男性吸入性损伤发病率高,火焰烧伤是吸入性损伤的主要原因。2000年以来,吸入性损伤死亡率较前期总体下降。