Department of Paediatric Rheumatology, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol BS2 8BJ, UK.
Rheumatology (Oxford). 2012 May;51(5):874-7. doi: 10.1093/rheumatology/ker441. Epub 2011 Dec 30.
To assess the safety and efficacy of US-guided CS injection done by a paediatric rheumatologist into the TM joints (TMJs) in children with JIA.
Children with JIA presenting to the rheumatology clinic were assessed for TMJ arthritis. Triamcinolone hexacetonide was injected in children with active arthritis assessed by MRI using US guidance under general anaesthesia by the same paediatric rheumatologist trained in the procedure. Efficacy and safety were assessed post-injection by patient-guided symptoms and physical examination.
Thirty-eight children (34 girls) with JIA who had TMJ injection done between January 2009 and January 2011 were included in the analysis. Mean age was 12.25 (± 3.55) (range 5-18) years. The mean disease duration was 4.54 (± 2.73) (range 1.5-11.1) years. Symptoms pre-injection were pain in 17/38 (44.7%), jaw deviation in 14/38 (36.8%), restricted jaw movement in 13/38 (34.2%) and chewing dysfunction in 7/38 (18.4%). Five (12.5%) children had micrognathia. A total of 63 joints were injected. The injection was efficacious in 58/63 (92.06%) joints. All 17 (100%) children had resolution of pain, and chewing dysfunction improved in 5/7 (71.4%). Jaw deviation improved in 13/14 (92.8%). In the 5/63 (7.9%) injections that were not efficacious, two children with both TMJs injected (four joints) had persisting stiffness with chewing dysfunction and one had persistent jaw deviation. One child developed a scar at the site of injection.
US-guided CS injection into the TMJ done by a paediatric rheumatologist trained in the procedure is safe with a high rate of success.
评估由儿科风湿病学家在关节镜引导下对患有幼年特发性关节炎(JIA)的儿童的 TM 关节(TMJ)进行 CS 注射的安全性和疗效。
在风湿病门诊就诊的患有 JIA 的儿童接受 TMJ 关节炎评估。在全身麻醉下,由接受过该程序培训的同一位儿科风湿病学家使用关节镜引导,对 MRI 评估有活动性关节炎的儿童进行曲安奈德六乙酸注射。注射后通过患者指导的症状和体格检查评估疗效和安全性。
2009 年 1 月至 2011 年 1 月间,共有 38 名(34 名女性)患有 JIA 的儿童接受 TMJ 注射,纳入分析。平均年龄为 12.25(±3.55)(5-18 岁)。平均病程为 4.54(±2.73)(1.5-11.1 岁)。注射前症状为 17/38(44.7%)疼痛,14/38(36.8%)下颌偏斜,13/38(34.2%)下颌运动受限,7/38(18.4%)咀嚼功能障碍。5(12.5%)名儿童有小颌畸形。共注射 63 个关节。63 个关节中有 58 个(92.06%)有效。17/17(100%)名儿童疼痛完全缓解,5/7(71.4%)例咀嚼功能障碍改善。14/14(92.8%)下颌偏斜改善。在 63 次注射中,有 5 次(7.9%)无效,其中 2 名双侧 TMJ 注射(4 个关节)的儿童仍有咀嚼功能障碍和僵硬,1 名儿童持续下颌偏斜。1 名儿童在注射部位出现疤痕。
由接受过该程序培训的儿科风湿病学家进行关节镜引导下 CS 注射 TMJ 是安全的,成功率高。