Searles J S, Alterman A I, Purtill J J
University of Pennsylvania, Philadelphia.
Alcohol Clin Exp Res. 1990 Aug;14(4):557-60. doi: 10.1111/j.1530-0277.1990.tb01199.x.
The Michigan Alcoholism Screening Test (MAST) and the MacAndrew Alcoholism Scale (MAC) were administered to forty-one schizophrenic inpatients also meeting DSM-III criteria for either alcohol abuse or alcohol dependence and 29 schizophrenic inpatients who did not qualify for an additional substance abuse diagnosis other than marijuana abuse/dependence. The MAC failed to differentiate between the alcoholic and nonalcoholic groups and both groups scored above the recommended cutting score. The MAST significantly differentiated the alcoholic and nonalcoholic schizophrenic patients and was as sensitive to a history of alcohol abuse as to alcohol dependence. Neither the MAST nor MAC was sensitive to recent versus more remote drinking. The overall classificatory accuracy of the MAST was found to be 80% and that of the MAC was 56%. A logistic regression analysis revealed that the use of just four MAST items can yield a group classificatory rate of 83%. It was concluded that the MAST exhibited sufficient sensitivity and specificity to be used as an initial screening instrument for alcoholism in schizophrenic patients.
密歇根酒精成瘾筛查测试（MAST）和麦安德鲁酒精成瘾量表（MAC）被施用于41名同时符合DSM-III酒精滥用或酒精依赖标准的精神分裂症住院患者，以及29名除大麻滥用/依赖外不符合其他物质滥用诊断标准的精神分裂症住院患者。MAC未能区分酗酒组和非酗酒组，两组得分均高于推荐的临界分数。MAST显著区分了酗酒和非酗酒的精神分裂症患者，对酒精滥用史和酒精依赖史同样敏感。MAST和MAC对近期饮酒与远期饮酒均不敏感。MAST的总体分类准确率为80%，MAC为56%。逻辑回归分析显示，仅使用MAST的四个项目即可产生83%的组分类率。研究得出结论，MAST表现出足够的敏感性和特异性，可作为精神分裂症患者酒精成瘾的初始筛查工具。
