Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA.
Mayo Clin Proc. 2012 Jan;87(1):41-9. doi: 10.1016/j.mayocp.2011.08.003.
To study characteristics and outcomes associated with emergency response team (ERT) activation in postsurgical patients discharged to regular wards after anesthesia.
We identified all ERT activations that occurred within 48 hours after surgery from June 1, 2008, through December 31, 2009, in patients discharged from the postanesthesia care unit to regular wards. For each ERT case, up to 2 controls matched for age (±10 years), sex, and type of procedure were identified. A chart review was performed to identify factors that may be associated with ERT activation.
We identified 181 postoperative ERT calls, 113 (62%) of which occurred within 12 hours of discharge from the postanesthesia care unit, for an incidence of 2 per 1000 anesthetic administrations (0.2%). Multiple logistic regression analysis revealed the following factors to be associated with increased odds for postoperative ERT activation: preoperative central nervous system comorbidity (odds ratio [OR], 2.53; 95% confidence interval [CI], 1.20-5.32; P=.01), preoperative opioid use (OR, 2.00; 95% CI, 1.30-3.10; P=.002), intraoperative use of phenylephrine infusion (OR, 3.05; 95% CI, 1.08-8.66; P=.04), and increased intraoperative fluid administration (per 500-mL increase, OR, 1.06; 95% CI, 1.01-1.12; P=.03). ERT patients had longer hospital stays, higher complication rates, and increased 30-day mortality compared with controls.
Preoperative opioid use, history of central neurologic disease, and intraoperative hemodynamic instability are associated with postoperative decompensation requiring ERT intervention. Patients with these clinical characteristics may benefit from discharge to progressive or intensive care units in the early postoperative period.
研究麻醉后术后患者出院至普通病房后,因紧急反应团队(ERT)激活而出现的特征和结果。
我们从 2008 年 6 月 1 日至 2009 年 12 月 31 日期间,确定了术后 48 小时内发生在从麻醉后护理病房出院至普通病房的患者的所有 ERT 激活情况。对于每个 ERT 病例,我们确定了最多 2 个与年龄(±10 岁)、性别和手术类型相匹配的对照病例。我们进行了病历回顾,以确定可能与 ERT 激活相关的因素。
我们共发现了 181 例术后 ERT 电话呼叫,其中 113 例(62%)发生在离开麻醉后护理病房后的 12 小时内,发病率为每 1000 次麻醉操作 2 次(0.2%)。多变量逻辑回归分析显示,以下因素与术后 ERT 激活的可能性增加有关:术前中枢神经系统合并症(比值比[OR],2.53;95%置信区间[CI],1.20-5.32;P=.01)、术前使用阿片类药物(OR,2.00;95% CI,1.30-3.10;P=.002)、术中使用苯肾上腺素输注(OR,3.05;95% CI,1.08-8.66;P=.04)和术中液体输入增加(每增加 500 毫升,OR,1.06;95% CI,1.01-1.12;P=.03)。ERT 患者的住院时间更长,并发症发生率更高,30 天死亡率也高于对照组。
术前使用阿片类药物、中枢神经系统疾病史和术中血流动力学不稳定与需要 ERT 干预的术后失代偿有关。具有这些临床特征的患者可能受益于在术后早期出院至进展或重症监护病房。