Division of Endocrinology, Department of Medicine, University of California, Irvine, Irvine, California, USA.
Clin Cancer Res. 2012 Jan 1;18(1):6-8. doi: 10.1158/1078-0432.CCR-11-2547.
Estrogen receptors at the plasma membrane and cytoplasm have been difficult to detect in breast cancer specimens. New imaging approaches are needed to determine the percentage of cancers expressing extranuclear estrogen receptors and their impact on cancer biology and treatment.
在乳腺癌标本中,很难检测到质膜和细胞质中的雌激素受体。需要新的成像方法来确定表达核外雌激素受体的癌症的百分比,以及它们对癌症生物学和治疗的影响。