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[预激综合征:儿科人群(86例)的长期随访研究]

[Wolff-Parkinson-White syndrome: long-term follow up study in a pediatric population (86 cases)].

作者信息

González de Dios J, Rodríguez Balo A, Martínez de Azagra Garde A, Benito Bartolomé F, Cabo Salvador J, Moreno Granado F

机构信息

Servicio de Cardiología, Clínica Infantil La Paz, Madrid.

出版信息

An Esp Pediatr. 1990 Jun;32(6):522-30.

PMID:2221629
Abstract

Eighty six patients (48 males and 38 females) with W-P-W diagnosed before the age of 15 years had a maximum follow-up of 20 years. The mean age at diagnosis was 3 y and 5 m., most cases being concentrated in the first 6 months of life (37%). Twenty seven (31.4%) had associated heart disease, the more common being: ventricular septal defect (6 cases), Ebstein malformation (5 cases) and transposition of the great arteries (4 cases). Supraventricular tachycardia (SVT) was the commonest form of clinical presentation, followed by examination because heart murmur or heart disease. Fifty patients (58%) had SVT along the follow-up. SVT was more frequent in W-P-W type A than in type B (p less than 0.05). There was a statistically significant correlation (p less than 0.001) between the association of SVT and the absence of heart disease, but the finding must be questioned because the true incidence of W-P-W in normal population is unknown. There also were a significant correlation (p less than 0.05) between the association of W-P-W type B and the presence of heart disease. An electrophysiologic study was performed in 11 patients, 6 of them being concealed W-P-W. Four patients were operated upon because of SVT. We have studied a total of 154 SVT episodes in the 50 patients with SVT. The treatment more frequently used to finish the SVT included: verapamil, DC-Countershock and Digoxin.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

86例15岁前确诊为预激综合征(W-P-W)的患者,最长随访20年。确诊时的平均年龄为3岁5个月,大多数病例集中在出生后的前6个月(37%)。27例(31.4%)伴有心脏病,较常见的有:室间隔缺损(6例)、埃布斯坦畸形(5例)和大动脉转位(4例)。室上性心动过速(SVT)是最常见的临床表现形式,其次是因心脏杂音或心脏病而接受检查。50例(58%)患者在随访期间出现SVT。A型预激综合征患者发生SVT的频率高于B型(p<0.05)。SVT与无心脏病之间存在统计学显著相关性(p<0.001),但由于正常人群中预激综合征的真实发病率未知,这一发现值得质疑。B型预激综合征与心脏病的存在之间也存在显著相关性(p<0.05)。对11例患者进行了电生理研究,其中6例为隐匿性预激综合征。4例患者因SVT接受了手术。我们共研究了50例SVT患者的154次SVT发作。最常用于终止SVT的治疗方法包括:维拉帕米、直流电复律和地高辛。(摘要截断于250字)

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