沙丁胺醇和吡布特罗口服对哮喘患者的 FEV1、心率和血压的影响。
Effects of oral salbutamol and pirbuterol on FEV1, heart rate and blood pressure in asthmatics.
机构信息
Respiratory Diseases Unit, Northern General Hospital Edinburgh EH5 2DQ.
出版信息
Br J Clin Pharmacol. 1976 Aug;3(4):595-600. doi: 10.1111/j.1365-2125.1976.tb04881.x.
Abstract
In a double-blind trial the effects on ventilatory function (FEV1), heart rate and blood pressure of oral pirbuterol and oral salbutamol in various single doses were studied in ten patients with chronic asthma. Pirbuterol (15 mg) and salbutamol (4 mg) produced equal peak levels of bronchodilatation. There was no significant difference in the mean rise in heart rates caused by the two drugs, and no other significant side-effects were noted.
摘要
在一项双盲试验中，我们研究了 10 名慢性哮喘患者口服吡布特罗和沙丁胺醇在不同单剂量下对通气功能（FEV1）、心率和血压的影响。吡布特罗（15 毫克）和沙丁胺醇（4 毫克）产生了同等的支气管扩张峰值水平。两种药物引起的平均心率升高没有显著差异，也没有注意到其他显著的副作用。
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