Institute of Biomedical Investigations August Pi i Sunyer, Calle Mallorca 183, Barcelona, Spain.
Diabetes Technol Ther. 2012 Apr;14(4):373-8. doi: 10.1089/dia.2011.0233. Epub 2012 Jan 4.
A strong correlation exists between improved blood glucose control, obtained from the earliest stages of diabetes, and the prevention of complications. However, tight glycometabolic control does not always translate into an advantage for every patient. Because the characteristics of individual patients play an important role in diabetes care, there is a need to develop personalized action plans. This article suggests tailored therapeutic algorithms for some of the commonest type 2 diabetes phenotypes, taking into consideration age, body mass index, presence of micro- and macrovascular complications, hypoglycemia risk, and the co-existence of chronic renal failure. Particular emphasis is placed on exploiting information supplied through the rational use of self-monitoring of blood glucose as a tool for optimizing diabetes management, according to the prevalence of fasting/preprandial or postprandial hyperglycemia.
改善血糖控制与预防并发症之间存在很强的相关性,这种改善可以在糖尿病的早期阶段获得。然而,严格的血糖控制并不总是对每个患者都有优势。由于个体患者的特点在糖尿病治疗中起着重要作用,因此需要制定个性化的行动计划。本文针对一些最常见的 2 型糖尿病表型,考虑到年龄、体重指数、微血管和大血管并发症的存在、低血糖风险以及慢性肾衰竭的共存情况,提出了针对这些表型的个体化治疗算法。本文特别强调通过合理利用自我血糖监测来优化糖尿病管理,根据空腹/餐前或餐后高血糖的流行情况,利用自我血糖监测提供的信息。