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一种在院前环境中维持冷藏生理盐水的简单方法。

A simple method of maintaining chilled saline in the prehospital setting.

机构信息

Department of Emergency Medicine, Mercy Catholic Medical Center, Philadelphia, PA 19143, USA.

出版信息

Am J Emerg Med. 2012 Oct;30(8):1385-8. doi: 10.1016/j.ajem.2011.10.007. Epub 2012 Jan 2.

Abstract

OBJECTIVE

Mild therapeutic hypothermia has been shown to improve neurologic outcomes after sudden cardiac arrest. Therapeutic hypothermia should be started as soon as return of spontaneous circulation occurs. However, saline is difficult to keep chilled in the prehospital environment. We sought to determine whether a cooler and ice packs could keep saline cold under prehospital conditions.

METHODS

In phase 1 of the experiment, two 1000-mL bags of prechilled 0.9% normal saline were placed in a cooler with 3 ice packs. An additional bag of 1000-mL 0.9% normal saline remained outside the cooler as a control. Over 9 consecutive days, we measured the ambient air temperature and the temperature of each bag of saline every 4 hours. In phase 2 of the experiment, the cooler was kept sealed, and the temperature of the saline was measured after 24 hours.

RESULTS

The mean temperatures over 24 hours ranged as follows: ambient temperature, 24°C to 27.2°C; bottom bag, 0.6°C to 3.5°C; top bag, 1.4°C to 5.7°C; and control bag, 9.8°C to 26.8°C. A t test was used to compare the chilled saline against the control bag. Statistical significance (P < .05) was achieved at all times. In phase 2 of the experiment, after 24 hours, 100% of the bottom bags and 93% of the top bags were less than 6°C.

CONCLUSIONS

Our data demonstrate that saline can be kept chilled in ambulances for 24 hours using ice packs and coolers. The estimated cost is less than $50.00 per ambulance. Using coolers and ice packs is an inexpensive way for emergency medical service agencies to initiate prehospital hypothermia.

摘要

目的

轻度治疗性低温已被证明可改善心搏骤停后的神经功能结局。一旦自主循环恢复,就应开始进行治疗性低温。然而,在院前环境中,生理盐水很难保持冷藏。我们旨在确定冷藏器和冰袋是否可在院前条件下使生理盐水保持低温。

方法

在实验的第 1 阶段,将两袋 1000 毫升预冷的 0.9%生理盐水放入冷藏器中,并用 3 个冰袋。另一袋 1000 毫升 0.9%生理盐水放在冷藏器外作为对照。在连续 9 天内,我们每 4 小时测量一次环境空气温度和每个生理盐水袋的温度。在实验的第 2 阶段,冷藏器保持密封,24 小时后测量生理盐水的温度。

结果

24 小时内的平均温度如下:环境温度为 24°C 至 27.2°C;底部袋子为 0.6°C 至 3.5°C;顶部袋子为 1.4°C 至 5.7°C;对照袋子为 9.8°C 至 26.8°C。使用 t 检验比较冷藏生理盐水与对照袋。所有时间均达到统计学意义(P<.05)。在实验的第 2 阶段,24 小时后,100%的底部袋子和 93%的顶部袋子的温度均低于 6°C。

结论

我们的数据表明,在救护车中使用冰袋和冷藏器可将生理盐水冷藏 24 小时。估计成本为每辆救护车不到 50.00 美元。使用冷藏器和冰袋是急救医疗服务机构启动院前低温治疗的一种廉价方法。

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