Kiyosawa M, Bosley T M, Kushner M, Jamieson D, Alavi A, Reivich M
Department of Nuclear Medicine, University of Pennsylvania, Philadelphia.
Ann Neurol. 1990 Aug;28(2):180-3. doi: 10.1002/ana.410280212.
Eight patients were evaluated with 18F-fluorodeoxyglucose positron emission tomography between 3 and 30 days after isolated stroke involving the middle cerebral artery territory that caused homonymous hemianopia. Diffuse hypometabolism was present throughout the damaged cerebral hemisphere, even in cortical areas not obviously ischemic by clinical examination or neuro-imaging. Glucose metabolism in primary and association visual cortex of the damaged hemisphere was decreased by more than 47% (p less than 0.01). Metabolism in the undamaged hemisphere was less profoundly affected, but significant decrements were found in calcarine (40%; p less than 0.01) and lateral occipital cortex (35%; p less than 0.05).
对8例因大脑中动脉区域孤立性卒中导致同向偏盲的患者，在卒中后3至30天内进行了18F-氟脱氧葡萄糖正电子发射断层扫描评估。整个受损脑半球均出现弥漫性代谢减低，即使在临床检查或神经影像学检查中未发现明显缺血的皮质区域也是如此。受损半球的初级和联合视觉皮层的葡萄糖代谢降低超过47%（p<0.01）。未受损半球的代谢受影响程度较小，但在距状裂（40%；p<0.01）和枕外侧皮层（35%；p<0.05）发现有显著降低。
