Kiyosawa M, Mizuno K, Hatazawa J, Fukuda H, Yamada K, Ito M, Matsuzawa T, Watanuki S, Ido T
Am J Ophthalmol. 1986 Mar 15;101(3):310-9. doi: 10.1016/0002-9394(86)90826-3.
To evaluate the usefulness of metabolic mapping by positron emission tomography using 18F-deoxyfluoroglucose as a tracer in the diagnosis of hemianopsia, we examined eight patients who had had cerebrovascular accident, and four controls. Neuro-ophthalmologic examination disclosed hemianopsia in five and incomplete hemianopsia in three patients; computed tomography showed low-density areas in four patients; and nuclear magnetic resonance imaging demonstrated a prolonged T2 area in five patients. The cerebral metabolic rate for glucose without visual stimulation in the visual cortex was 7.4 +/- 1.0 mg/min/100 g of brain without interhemispheric asymmetry. Light stimulation increased cerebral metabolic rate for glucose in the visual cortex of the nonaffected hemisphere and decreased it in the affected hemisphere. Asymmetry in the metabolic rate in the posterior medial occipital cortex in complete hemianopsia was 22% 12% (P less than .01).
为了评估使用18F - 脱氧氟葡萄糖作为示踪剂的正电子发射断层扫描代谢图谱在偏盲诊断中的实用性，我们检查了8例脑血管意外患者和4例对照。神经眼科检查发现5例患者有偏盲，3例患者有不完全偏盲；计算机断层扫描显示4例患者有低密度区；核磁共振成像显示5例患者有T2延长区。视觉皮层在无视觉刺激时的脑葡萄糖代谢率为7.4±1.0mg/min/100g脑，无半球间不对称。光刺激增加了未受影响半球视觉皮层的脑葡萄糖代谢率，并降低了受影响半球的代谢率。完全偏盲患者枕叶后内侧代谢率的不对称性为22% 12%（P<0.01）。
