Department of Family Medicine, Medical University of South Carolina, Charleston, USA.
J Am Board Fam Med. 2012 Jan-Feb;25(1):16-23. doi: 10.3122/jabfm.2012.01.110148.
The evidence of the relationship between fiber intake and control of diabetes is mixed. The purpose of this study was to determine if an increase in dietary fiber affects glycosylated hemoglobin (HbA1c) and fasting blood glucose in patients with type 2 diabetes mellitus.
Randomized studies published from January 1, 1980, to December 31, 2010, that involved an increase in dietary fiber intake as an intervention, evaluated HbA1c and/or fasting blood glucose as an outcome, and used human participants with known type 2 diabetes mellitus were selected for review.
Fifteen studies met inclusion and exclusion criteria. The overall mean difference of fiber versus placebo was a reduction of fasting blood glucose of 0.85 mmol/L (95% CI, 0.46-1.25). Dietary fiber as an intervention also had an effect on HbA1c over placebo, with an overall mean difference of a decrease in HbA1c of 0.26% (95% CI, 0.02-0.51).
Overall, an intervention involving fiber supplementation for type 2 diabetes mellitus can reduce fasting blood glucose and HbA1c. This suggests that increasing dietary fiber in the diet of patients with type 2 diabetes is beneficial and should be encouraged as a disease management strategy.
膳食纤维摄入量与糖尿病控制之间的关系证据不一。本研究旨在确定增加膳食纤维的摄入量是否会影响 2 型糖尿病患者的糖化血红蛋白(HbA1c)和空腹血糖。
本研究纳入了 1980 年 1 月 1 日至 2010 年 12 月 31 日期间发表的随机对照研究,这些研究以增加膳食纤维摄入作为干预措施,以 HbA1c 和/或空腹血糖作为结局指标,并使用已知患有 2 型糖尿病的人类参与者。
符合纳入和排除标准的研究共有 15 项。纤维与安慰剂相比,总体平均差异为空腹血糖降低 0.85mmol/L(95%CI,0.46-1.25)。膳食纤维作为一种干预措施,对 HbA1c 也有影响,与安慰剂相比,HbA1c 的总体平均差异降低了 0.26%(95%CI,0.02-0.51)。
总的来说,涉及 2 型糖尿病患者补充膳食纤维的干预措施可以降低空腹血糖和 HbA1c。这表明增加 2 型糖尿病患者饮食中的膳食纤维是有益的,应作为一种疾病管理策略加以鼓励。