Vignaud J M, Plenat F, Duprez A
Laboratoire d'Anatomie Pathologique, Faculté de Médecine, Vandceuvre-Lès-Nancy, France.
Arch Anat Cytol Pathol. 1990;38(4):125-34.
In situ hybridization is used to localize DNA or RNA sequences in tissue sections, single cells or chromosome preparations. The preparation and labeling of probes and the main steps of the technique are described and discussed together with its main applications.
原位杂交用于在组织切片、单细胞或染色体标本中定位DNA或RNA序列。本文介绍并讨论了探针的制备与标记、该技术的主要步骤及其主要应用。
