Situm Mirna, Bolanca Zeljana, Kolić Maja, Gulin Sanda Jerković, Gulin Damir
Department of Dermatovenerology, "Sestre milosrdnice" University Hospital Center, Zagreb, Croatia.
Coll Antropol. 2011 Sep;35 Suppl 2:107-9.
The aim of the study was to analyze the clinical prevalence and pathohistological correlation of dysplastic nevi. In the period between 2000 and 2009, in the Outpatient Clinic of Referral Centre for Melanoma of the Ministry of Health and Social Welfare of the Republic of Croatia, 12,344 patients were examined, and 35.07% of them were surgically removed in the same institution. Among the patients, 69.16% had clinically diagnosed melanocytic tumor. Out of them, 28.39% were dysplastic. Dysplastic nevus was pathohistologically diagnosed in 20.02% of pathohistologically diagnosed melanocytic tumors. There was women predominace among patients with clinically diagnosed dysplastic nevi (65.22%). The most frequent localization was the trunk in both sexes, women 78.18%, men 76.75%. The coincidence of clinical and pathohistological diagnosis of dysplastic nevus was 30.70%. The results of this study, based on a large number of patients could be a significant contribution in understanding characteristics of dysplastic nevus, its clinical and pathohistological complexity. We hope that the data will contribute to the creation of general accepted protocols in the diagnostics of dysplastic nevus.
本研究的目的是分析发育异常痣的临床患病率及其病理组织学相关性。在2000年至2009年期间,克罗地亚共和国卫生和社会福利部黑色素瘤转诊中心门诊对12344例患者进行了检查,其中35.07%的患者在该机构接受了手术切除。在这些患者中,69.16%临床诊断为黑素细胞肿瘤。其中,28.39%为发育异常性。在病理组织学诊断的黑素细胞肿瘤中,20.02%病理组织学诊断为发育异常痣。临床诊断为发育异常痣的患者中女性占优势(65.22%)。男女最常见的部位均为躯干,女性为78.18%,男性为76.75%。发育异常痣临床与病理组织学诊断的符合率为30.70%。本研究基于大量患者的结果,可能对理解发育异常痣的特征及其临床和病理组织学复杂性有重要贡献。我们希望这些数据将有助于制定发育异常痣诊断方面普遍接受的方案。