Novak-Stroligo Maja, Alpeza-Dunato Zvjezdana, Kovacević Damir, Caljkusić-Mance Tea
Department of Ophtalmology, Rijeka University Hospital Center, Rijeka, Croatia.
Coll Antropol. 2011 Sep;35 Suppl 2:305-6.
Central corneal thickness is very important measurement in glaucoma treatment because it influences the eye pressure measurements. A thinner cornea gives us artifactually lower intraocular pressure and a thicker cornea gives higher intraocular pressure reading, so it has to be corrected in both cases. The aim of this study is to compare central corneal thickness between congenital glaucoma patients and normal subjects. Prospective study included 27 patients with congenital glaucoma and 35 patients in control group. First group was subdivided in two subgroups: A--8 earlier operated patients, B--19 patients treated with topic therapy. Patients had no other corneal disorders, history of trauma, corneal surgery and they were not contact lens wearers. Measurements were performed by specular microscope Tomey EM 3000 on central corneas. This study showed that patients with congenital glaucoma have lower central corneal thickness than normal subjects. Also, the study showed that antiglaucomatous operation doesn't influence central corneal thickness. Central corneal thickness need to be a routine part of examination measurements because of need to correct intraocular pressure according to it, but also the thinner corneas values can suggest congenital glaucoma diagnosis beside the other parameters.
中央角膜厚度在青光眼治疗中是一项非常重要的测量指标，因为它会影响眼压测量结果。角膜较薄会使我们测得的眼压值人为偏低，而角膜较厚则会使眼压读数偏高，所以在这两种情况下都必须进行校正。本研究的目的是比较先天性青光眼患者与正常受试者的中央角膜厚度。前瞻性研究纳入了27例先天性青光眼患者和35例对照组患者。第一组又分为两个亚组：A组——8例早期接受手术的患者，B组——19例接受局部治疗的患者。患者无其他角膜疾病、外伤史、角膜手术史，且不佩戴隐形眼镜。使用Tomey EM 3000型镜面显微镜对中央角膜进行测量。本研究表明，先天性青光眼患者的中央角膜厚度低于正常受试者。此外，该研究还表明抗青光眼手术不会影响中央角膜厚度。由于需要根据中央角膜厚度校正眼压，而且除其他参数外，较薄的角膜厚度值也可能提示先天性青光眼的诊断，所以中央角膜厚度应成为检查测量的常规组成部分。
