Department of Neurology, University of Erlangen-Nuremberg, Erlangen, Germany.
Eur J Neurol. 2012 Nov;19(11):1477-81. doi: 10.1111/j.1468-1331.2011.03628.x. Epub 2012 Jan 4.
Clinical data on sex differences in perihemorrhagic edema (PHE) after intracerebral hemorrhage (ICH) are lacking.
Patients with spontaneous supratentorial ICH who had received standard conservative treatment were identified retrospectively. PHE development was assessed over a 14-day period on follow-up CT scans (days 1, 2-4, 5-7, 8-11, and 12-14). ICH and PHE volumes were assessed semiautomatically and compared between men and women.
A total of 387 patients (233 men) were included. Starting at days 2-4, women showed lower PHE values (P < 0.05; days 2-4, 8-11) or a trend toward significance (P ≤ 0.1; days 5-7, 12-14).
Female sex may predict lower PHE volumes.
关于脑出血（ICH）后围出血性水肿（PHE）的性别差异的临床数据尚缺乏。
我们回顾性地确定了接受标准保守治疗的自发性幕上 ICH 患者。在随访 CT 扫描上（第 1、2-4、5-7、8-11 和 12-14 天）评估 14 天期间 PHE 的发展情况。我们采用半自动方法评估 ICH 和 PHE 体积，并比较男性和女性之间的差异。
共纳入 387 例患者（233 例男性）。从第 2-4 天开始，女性的 PHE 值较低（P<0.05；第 2-4、8-11 天）或呈显著趋势（P≤0.1；第 5-7、12-14 天）。
女性性别可能预示着较低的 PHE 体积。
