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肝包虫病:丹麦一家三级转诊中心的经验(2002-2010 年)。

Cystic echinococcosis of the liver: experience from a Danish tertiary reference center (2002-2010).

机构信息

Department of Radiology, Rigshospitalet, Copenhagen OE, Denmark.

出版信息

J Travel Med. 2012 Jan-Feb;19(1):28-34. doi: 10.1111/j.1708-8305.2011.00577.x. Epub 2011 Dec 8.

DOI:10.1111/j.1708-8305.2011.00577.x
PMID:22221809
Abstract

BACKGROUND

Cystic echinococcosis (CE) of the liver can be treated with ultrasound-guided puncture, aspiration, injection, and re-aspiration (PAIR), with surgery and with benzimidazole derivatives. The aim of this study was to review available data concerning treatment modality and outcome for patients treated for CE of the liver in a Danish tertiary reference center.

METHODS

A search was made for patients treated for CE infection between January 1, 2002 and January 1, 2010. All relevant patient records and radiology exams were scrutinized and all cysts were re-classified according to the WHO-IWGE, blinded as to which treatment the patient had received. PAIR was performed as a first choice treatment and surgery was reserved for cases where PAIR was impossible. Inactive cyst stages received medical treatment only.

RESULTS

The search revealed 26 cases with confirmed CE of the liver. Nine patients underwent PAIR and nine patients surgery as a first choice treatment. Three patients were treated with PAIR secondary to surgery and one patient was treated with surgery secondary to PAIR. For all PAIR treatments, the success rate was 58% regardless of cyst stage and for surgery the success rate was 70%. The difference between the rates was not statistically significant (p = 0.67).

CONCLUSION

CE is a rare disease in Denmark and our study is the first describing clinical management of CE in our institution.

摘要

背景

肝包虫病(CE)可以通过超声引导下穿刺、抽吸、注射和再抽吸(PAIR)、手术和苯并咪唑衍生物进行治疗。本研究旨在回顾在丹麦一家三级参考中心治疗肝包虫病患者的治疗方式和结果。

方法

检索 2002 年 1 月 1 日至 2010 年 1 月 1 日期间治疗的 CE 感染患者。仔细检查所有相关的患者记录和放射学检查,并根据世界卫生组织-国际包虫病工作组(WHO-IWGE)重新分类所有囊肿,对患者接受的治疗方法不设盲。PAIR 是首选治疗方法,手术保留给 PAIR 不可能的病例。非活动囊肿阶段仅接受药物治疗。

结果

检索结果显示 26 例确诊的肝包虫病患者。9 例患者接受 PAIR 治疗,9 例患者接受手术作为首选治疗。3 例患者因手术而接受 PAIR 治疗,1 例患者因 PAIR 而接受手术治疗。所有 PAIR 治疗的成功率为 58%,与囊肿阶段无关,而手术的成功率为 70%。两者之间的差异无统计学意义(p=0.67)。

结论

CE 在丹麦是一种罕见疾病,我们的研究首次描述了我们机构中 CE 的临床管理。

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