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颗粒物空气污染与温带澳大利亚城市的心肺疾病入院率:病例交叉分析。

Particulate air pollution and cardiorespiratory hospital admissions in a temperate Australian city: A case-crossover analysis.

机构信息

Discipline of Public Health, The University of Adelaide, Adelaide, South Australia, Australia.

出版信息

Sci Total Environ. 2012 Feb 1;416:48-52. doi: 10.1016/j.scitotenv.2011.09.027. Epub 2012 Jan 4.

DOI:10.1016/j.scitotenv.2011.09.027
PMID:22221868
Abstract

BACKGROUND

Although ambient air pollution exposure has been linked with poor health in many parts of the world, no previous study has investigated the effect on morbidity in the city of Adelaide, South Australia.

OBJECTIVE

To explore the association between particulate matter (PM) and hospitalisations, including respiratory and cardiovascular admissions in Adelaide, South Australia.

METHODS

For the study period September 2001 to October 2007, daily counts of all-cause, cardiovascular and respiratory hospital admissions were collected, as well as daily air quality data including concentrations of particulates, ozone and nitrogen dioxide. Visibility codes for present weather conditions identified days when airborne dust or smoke was observed. The associations between PM and hospitalisations were estimated using time-stratified case-crossover analyses controlling for covariates including temperature, relative humidity, other pollutants, day of the week and public holidays.

RESULTS

Mean PM(10) concentrations were higher in the warm season, whereas PM(2.5) concentrations were higher in the cool season. Hospital admissions were associated with PM(10) in the cool season and with PM(2.5) in both seasons. No significant effect of PM on all-age respiratory admissions was detected, however cardiovascular admissions were associated with both PM(2.5) and PM(10) in the cool season with the highest effects for PM(2.5) (4.48%, 95% CI: 0.74%, 8.36% increase per 10μg/m(3) increase in PM(2.5)).

CONCLUSION

These findings suggest that despite the city's relatively low levels of air pollution, PM concentrations are associated with increases in morbidity in Adelaide. Further studies are needed to investigate the sources of PM which may be contributing to the higher cool season effects.

摘要

背景

尽管在世界许多地区,环境空气污染暴露与健康状况不佳有关,但以前没有研究调查过其对南澳大利亚阿德莱德市发病率的影响。

目的

探讨南澳大利亚阿德莱德市空气中颗粒物(PM)与住院率的关系,包括呼吸系统和心血管系统疾病的住院率。

方法

在 2001 年 9 月至 2007 年 10 月的研究期间,收集了所有原因、心血管和呼吸系统疾病的住院人数的每日计数,以及包括颗粒物、臭氧和二氧化氮浓度在内的每日空气质量数据。根据天气状况的能见度代码,确定了观察到空气中灰尘或烟雾的天数。使用时间分层病例交叉分析方法,控制温度、相对湿度、其他污染物、星期几和公共假日等协变量,估计 PM 与住院率之间的关系。

结果

PM(10)浓度在温暖季节较高,而 PM(2.5)浓度在凉爽季节较高。住院人数与凉爽季节的 PM(10)以及两个季节的 PM(2.5)有关。未发现 PM 对全年龄段呼吸系统疾病住院的显著影响,但心血管疾病住院与凉爽季节的 PM(2.5)和 PM(10)有关,PM(2.5)的影响最大(每增加 10μg/m3,增加 4.48%,95%CI:0.74%,8.36%)。

结论

这些发现表明,尽管该市的空气污染水平相对较低,但 PM 浓度与阿德莱德市发病率的增加有关。需要进一步研究以调查可能导致凉爽季节影响较高的 PM 来源。

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