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利用 DNA 微阵列理解高海藻糖积累引起的酿酒酵母耐热性的机制。

Understanding the mechanism of heat stress tolerance caused by high trehalose accumulation in Saccharomyces cerevisiae using DNA microarray.

机构信息

Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita,Osaka 565-0871, Japan.

出版信息

J Biosci Bioeng. 2012 Apr;113(4):526-8. doi: 10.1016/j.jbiosc.2011.11.028. Epub 2012 Jan 4.

DOI:10.1016/j.jbiosc.2011.11.028
PMID:22222142
Abstract

DNA microarray analysis was performed to examine the stress tolerance mechanism of a Saccharomyces cerevisiae recombinant strain exhibiting high trehalose accumulation and heat stress tolerance. Results suggest that the upregulation of sugar transporter genes is one of the key events for heat stress tolerance of the recombinant strain.

摘要

采用 DNA 微阵列分析方法，研究了一株具有高海藻糖积累和耐热性的酿酒酵母重组菌株的应激耐受机制。结果表明，糖转运蛋白基因的上调是该重组菌株耐热性的关键事件之一。

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