双源 64 层腺苷负荷 CT 灌注与门控 SPECT-MPI 比较，评估左心室功能和容积。

Comparison of dual-source 64-slice adenosine stress CT perfusion with stress-gated SPECT-MPI for evaluation of left ventricular function and volumes.

机构信息

Cardiac MRI/PET/CT Program, Department of Radiology, Massachusetts General Hospital, Harvard Medical School 165 Cambridge Street, Suite 400, Boston, MA 02114, USA.

出版信息

J Cardiovasc Comput Tomogr. 2012 Jan-Feb;6(1):24-30. doi: 10.1016/j.jcct.2011.10.016. Epub 2011 Nov 18.

DOI:10.1016/j.jcct.2011.10.016

PMID:22222164

Abstract

BACKGROUND

Evaluation of left ventricular (LV) volumes and ejection fraction (LVEF) represent important components of pharmacologic stress imaging with either myocardial CT perfusion (CTP) or gated single-photon emission CT (SPECT) myocardial perfusion imaging (SPECT-MPI).

OBJECTIVES

We compared measurements of left ventricular function and volumes obtained with CTP and SPECT-MPI.

METHODS

Forty-seven patients (mean age, 62 ± 11 years; male, n = 39) underwent stress CTP and SPECT-MPI. LVEF (in %), end-systolic volume (ESV; in mL), and end-diastolic volume (EDV; in mL) derived from stress CTP images were compared with SPECT-MPI.

RESULTS

Stress CTP was in good agreement with SPECT-MPI for quantification of LVEF (r = 0.91), EDV (r = 0.75), and ESV (r = 0.83; all P < 0.001). The mean LVEF measured by stress CTP (66% ± 17%) was similar to SPECT-MPI (64% ± 15%). Similar values were also derived for mean EDV (123 ± 30 mL vs 120 ± 34 mL) and ESV (44 ± 28 mL vs 51 ± 34 mL) for CTP and SPECT-MPI, respectively. Good agreement was also shown between both techniques for the assessment of regional wall motion with identical wall motion scores in 95.3% of the segments (κ = 0.79).

CONCLUSIONS

LVEF and LV volume parameters as determined by dual-source 64-slice adenosine stress CTP show a high correlation with values obtained with stress-gated SPECT-MPI.

摘要

背景

左心室（LV）容积和射血分数（LVEF）的评估是使用心肌 CT 灌注（CTP）或门控单光子发射 CT（SPECT）心肌灌注成像（SPECT-MPI）进行药物负荷成像的重要组成部分。

目的

我们比较了 CTP 和 SPECT-MPI 获得的左心室功能和容积测量值。

方法

47 例患者（平均年龄 62 ± 11 岁；男性 n = 39）接受了应激 CTP 和 SPECT-MPI 检查。比较应激 CTP 图像得出的 LVEF（%）、收缩末期容积（ESV；mL）和舒张末期容积（EDV；mL）与 SPECT-MPI 的结果。

结果

应激 CTP 与 SPECT-MPI 在心功能 LVEF（r = 0.91）、EDV（r = 0.75）和 ESV（r = 0.83；均 P < 0.001）的定量方面具有良好的一致性。应激 CTP 测量的平均 LVEF（66% ± 17%）与 SPECT-MPI 相似（64% ± 15%）。CTP 和 SPECT-MPI 的平均 EDV（123 ± 30 mL 与 120 ± 34 mL）和 ESV（44 ± 28 mL 与 51 ± 34 mL）也得出了相似的值。两种技术在评估节段性壁运动方面也具有良好的一致性，95.3%的节段壁运动评分相同（κ = 0.79）。