Section of Otolaryngology-Head and Neck Surgery, Department of Surgery, Yale University School of Medicine, New Haven, CT 06510, USA.
Int Forum Allergy Rhinol. 2012 May-Jun;2(3):264-8. doi: 10.1002/alr.21012. Epub 2012 Jan 6.
Sinonasal Schwannomas represent less than 4% of all head and neck Schwannomas. These neural sheath tumors arise from the ophthalmic and maxillary divisions of the trigeminal nerve, as well as autonomic nerves from sympathetic fibers of the carotid plexus and parasympathetic fibers of the sphenopalatine ganglion. Patients commonly present with nonspecific symptoms such as nasal obstruction, epistaxis, and anosmia. Nasal endoscopy usually reveals a unilateral polypoid mass. Diagnostic imaging with computed tomography (CT) and magnetic resonance (MR) is typically nonspecific. Diagnosis may be delayed due to the masquerade of common sinonasal conditions, such as allergic rhinitis and chronic rhinosinusitis. We report a case involving a 51-year-old male with an anterior skull-base Schwannoma that was excised endoscopically. Clinical features, imaging characteristics, histopathology, and treatment of sinonasal Schwannomas are discussed.
鼻窦神经鞘瘤占头颈部神经鞘瘤的比例不足 4%。这些神经鞘肿瘤起源于三叉神经的眼神经和上颌神经分支，以及颈动脉丛的交感神经纤维和蝶腭神经节的副交感神经纤维。患者常表现出非特异性症状，如鼻塞、鼻出血和嗅觉丧失。鼻内镜检查通常显示单侧息肉样肿块。计算机断层扫描（CT）和磁共振（MR）的诊断成像通常无特异性。由于常见的鼻-鼻窦疾病（如变应性鼻炎和慢性鼻-鼻窦炎）的伪装，可能会导致诊断延迟。我们报告了一例 51 岁男性前颅底神经鞘瘤，经内镜切除。讨论了鼻窦神经鞘瘤的临床特征、影像学特征、组织病理学和治疗。
