Department of Gynecology and Obstetrics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, PR China.
Ultrasound Obstet Gynecol. 2012 Jul;40(1):93-8. doi: 10.1002/uog.11085.
To investigate the accuracy of transvaginal three-dimensional hysterosalpingo-contrast sonography using SonoVue (3D SonoVue-HyCoSy) in the assessment of Fallopian tubal patency.
We recruited 75 infertile patients undergoing 3D SonoVue-HyCoSy before standard diagnostic laparoscopy with chromotubation (lap and dye). Tubal patency was assessed by automated 3D coded contrast imaging (3D SonoVue-HyCoSy), and the findings were compared with the results of lap and dye.
For detecting tubal patency among the 150 Fallopian tubes assessed, 3D SonoVue-HyCoSy had a sensitivity of 93.5%, specificity of 86.3%, positive and negative predictive values of 87.8% and 92.6%, respectively, and diagnostic accuracy of 90.0%. The test-positive rates of 3D SonoVue-HyCoSy vs lap and dye were not significantly different (82/150 vs 77/150, P > 0.05).
3D SonoVue-HyCoSy should be considered clinically valuable as a practical, non-invasive, primary investigatory tool for evaluating tubal patency.
探讨三维经阴道超声造影（3D SonoVue-HyCoSy）联合声诺维（SonoVue）评估输卵管通畅性的准确性。
我们招募了 75 名接受标准诊断性腹腔镜检查联合输卵管通液术（腹腔镜下通染术）的不孕患者。采用自动三维编码对比成像（3D SonoVue-HyCoSy）评估输卵管通畅性，并将结果与腹腔镜下通染术的结果进行比较。
在评估的 150 条输卵管中，3D SonoVue-HyCoSy 检测输卵管通畅的敏感度为 93.5%，特异度为 86.3%，阳性预测值和阴性预测值分别为 87.8%和 92.6%，诊断准确性为 90.0%。3D SonoVue-HyCoSy 与腹腔镜下通染术的阳性检出率无显著差异（82/150 比 77/150，P>0.05）。
3D SonoVue-HyCoSy 可作为一种实用、无创的初步检查工具，用于评估输卵管通畅性，具有重要的临床价值。
