淋巴细胞生物学中的 Krüppel 样因子。
Krüppel-like factors in lymphocyte biology.
机构信息
Department of Laboratory Medicine and Pathology, Center for Immunology, University of Minnesota, Minneapolis, MN 55414, USA.
出版信息
J Immunol. 2012 Jan 15;188(2):521-6. doi: 10.4049/jimmunol.1101530.
Abstract
The Krüppel-like factor family of transcription factors plays an important role in differentiation, function, and homeostasis of many cell types. While their role in lymphocytes is still being determined, it is clear that these factors influence processes as varied as lymphocyte quiescence, trafficking, differentiation, and function. This review will present an overview of how these factors operate and coordinate with each other in lymphocyte regulation.
摘要
Krüppel 样转录因子家族在许多细胞类型的分化、功能和稳态中发挥着重要作用。虽然它们在淋巴细胞中的作用仍在确定之中，但很明显，这些因子影响着淋巴细胞静止、迁移、分化和功能等多种过程。本文综述了这些因子在淋巴细胞调控中如何相互作用和协调的机制。
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