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印度预防母婴传播服务、干预措施、覆盖率及利用情况研究。

Studying PPTCT Services, Interventions, Coverage and Utilization in India.

作者信息

Joshi Urvish, Patel Shilpa, Shah Kartik, Oza Umesh, Modi Heena

机构信息

Department of Community Medicine, AMC MET Medical College & LG Hospital, Maninagar, Ahmedabad, India.

出版信息

J Glob Infect Dis. 2011 Oct;3(4):371-7. doi: 10.4103/0974-777X.91062.

Abstract

BACKGROUND AND OBJECTIVES

Risk of vertical transmission (largest source of HIV in children) reduces from 33% to 3% with effective PPTCT interventions. NACP III has got an objective of testing all pregnant women for earliest linkage with PMTCT. Study was carried out to find out PPTCT service coverage, drop-outs, interventions efficacy with other determinants.

MATERIALS AND METHODS

At ICTCs, registered ANCs are counseled and tested for HIV. HIV+ve ANCs are linked to services and followed-up for institutional delivery, sdNVP, nutrition and children testing. HIV+ve ANCs since 2004 subsequently delivered till December 2009 and their exposed children in PPTCT-VSGH constituted study cohort.

RESULTS

29281 ANCs registered, 69.7% were counseled pre-test, 100% of them tested, 94.9% were counseled post-test. 60.5% were detected in 3(rd) trimester. CD4 testing was carried out in 71.6% HIV+ve ANCs. 81 ANCs were detected HIV+ve inclusive of 11 unregistered cases. 72 pregnancy outcomes reported institutionally, 77.6% were caesarian sections. Out of 59 live births, 56 sdNVP-MB-Pair were given. 88.1% children were traced till 18 months, 76.3% of live births were alive, 40.7% of live births were tested. 1 was found HIV+ve with history of adherence to all prescribed PPTCT guidelines.

CONCLUSIONS

PMTCT services - counseling and testing should be provided to all ANCs. EDD-based tracking, institutional deliveries, postnatal counseling to be encouraged along with complete MB pair coverage, capacity building of concerned staff regarding delivery of HIV+ve ANCs and exposed children tracking.

摘要

背景与目的

通过有效的预防母婴传播(PMTCT)干预措施,垂直传播风险(儿童感染HIV的最大来源)从33%降至3%。国家艾滋病控制项目三期的目标是对所有孕妇进行检测,以便尽早与预防母婴传播服务建立联系。开展本研究以了解预防母婴传播服务的覆盖情况、失访情况、干预效果及其他相关因素。

材料与方法

在综合咨询与检测中心,对登记在册的产前保健(ANC)妇女进行HIV咨询和检测。HIV检测呈阳性的产前保健妇女被转介至相关服务机构,并对其进行住院分娩、单剂量奈韦拉平(sdNVP)、营养及儿童检测方面的随访。2004年以来HIV检测呈阳性的产前保健妇女,其后直至2009年12月分娩的情况,以及她们在预防母婴传播-维多利亚女王医院的暴露儿童构成了研究队列。

结果

登记了29281名产前保健妇女,69.7%在检测前接受了咨询,100%进行了检测,94.9%在检测后接受了咨询。60.5%在孕晚期被检测出。71.6%的HIV检测呈阳性的产前保健妇女进行了CD4检测。共检测出81名HIV检测呈阳性的产前保健妇女,其中包括11例未登记病例。报告有72例住院分娩结局,77.6%为剖宫产。在59例活产中,给予了56对sdNVP-母亲-婴儿组合。88.1%的儿童随访至18个月,76.3%的活产婴儿存活,40.7%的活产婴儿接受了检测。发现1例HIV检测呈阳性儿童,其母亲有遵守所有规定的预防母婴传播指南的记录。

结论

应为所有产前保健妇女提供预防母婴传播服务——咨询和检测。应鼓励基于预产期的追踪、住院分娩、产后咨询,同时确保完整的母亲-婴儿组合覆盖,加强相关工作人员在处理HIV检测呈阳性的产前保健妇女及追踪暴露儿童方面的能力建设。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46c7/3249994/dc0667185f34/JGID-3-371-g004.jpg

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