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预防母婴传播服务与干预措施——覆盖情况与利用情况:印度古吉拉特邦的队列分析

Prevention of parent to child transmission services and interventions - coverage and utilization: A cohort analysis in Gujarat, India.

作者信息

Joshi Urvish, Kadri Amimuddin, Bhojiya Sudeshna

机构信息

Department of Community Medicine, Smt. NHL Municipal Medical College, Ahmedabad, Gujarat, India.

出版信息

Indian J Sex Transm Dis AIDS. 2010 Jul;31(2):92-8. doi: 10.4103/0253-7184.74983.

Abstract

BACKGROUND AND OBJECTIVES

Risk of vertical transmission (largest source of HIV in children) reduces from 33% to 3% with effective prevention of mother to child transmission (PMTCT) interventions. NACP-III has got an objective of testing all pregnant women for earliest linkage with PMTCT. Study was carried out to find out PPTCT service coverage, dropouts, intervention efficacy with other determinants.

MATERIALS AND METHODS

At ICTCs, registered ANCs are counseled and tested for HIV. HIV +ve ANCs are additionally linked to services and followed-up for institutional delivery, sdNVP, nutrition and children testing. HIV +ve ANCs since 2005 subsequently delivered till June 2008 and their exposed children in Gujarat's category A, B districts constituted study cohort.

RESULTS

259622 pregnant women registered, 72.1% were counseled pre-test, 83.4% of them tested, 74.4% received post-test counseling. 541 ANCs were detected HIV+ve. 45.5% delivered institutionally, 12.8% were unregistered. 12.1% were cesarian section and 66% delivered vaginally. 96.8% were live births, 92.13% mother-baby pair received sdNVP. 35% children could be traced till 18 months, 89% were alive. 90% were tested, 3 were found HIV +ve. Of them, none received MB Pair. Two were delivered vaginally, two received mixed feeding, two children's mothers were not linked with ART.

CONCLUSIONS

PMTCT services - counseling and testing should be provided to all ANCs. EDD-based tracking, institutional deliveries, postnatal counseling to be encouraged along with complete MB pair coverage, capacity building of concerned staff regarding delivery of HIV+ve ANCs and exposed children tracking.

摘要

背景与目的

通过有效的预防母婴传播(PMTCT)干预措施,垂直传播风险(儿童感染艾滋病毒的最大来源)从33%降至3%。国家艾滋病控制项目三期的目标是对所有孕妇进行检测,以便尽早与PMTCT建立联系。开展该研究以了解预防母婴传播服务的覆盖情况、失访情况、干预效果及其他决定因素。

材料与方法

在综合咨询与检测中心,对登记的产前检查孕妇进行艾滋病咨询和检测。艾滋病毒检测呈阳性的产前检查孕妇还会被转介至相关服务机构,并接受关于机构分娩、单剂量奈韦拉平、营养和儿童检测的随访。2005年以来艾滋病毒检测呈阳性的产前检查孕妇随后分娩至2008年6月,其在古吉拉特邦A、B类地区的受感染儿童构成研究队列。

结果

登记孕妇259622例,72.1%在检测前接受咨询,其中83.4%进行了检测,74.4%接受了检测后咨询。检测出541例产前检查孕妇艾滋病毒呈阳性。45.5%在机构分娩,12.8%未登记。12.1%为剖宫产,66%经阴道分娩。96.8%为活产,92.13%的母婴对接受了单剂量奈韦拉平。35%的儿童追踪至18个月,89%存活。90%接受检测,3例艾滋病毒呈阳性。其中,无人接受母婴对治疗。2例经阴道分娩,2例接受混合喂养,2例儿童的母亲未接受抗逆转录病毒治疗。

结论

应向所有产前检查孕妇提供预防母婴传播服务——咨询和检测。应鼓励基于预产期的追踪、机构分娩、产后咨询,同时确保完全覆盖母婴对,加强相关工作人员在艾滋病毒检测呈阳性的产前检查孕妇分娩及受感染儿童追踪方面的能力建设。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c8/3122599/4a71b1290ac1/IJSTD-31-92-g001.jpg

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