Restrepo Carlos S, Chen Melissa M, Martinez-Jimenez Santiago, Carrillo Jorge, Restrepo Catalina
Carlos S Restrepo, Melissa M Chen, Santiago Martinez-Jimenez, Jorge Carrillo, Catalina Restrepo, Department of Radiology, The University of Texas Health Science Center at San Antonio, Mail Code 7800, 7703 Floyd Curl Drive, San Antonio, TX 78229, United States.
World J Radiol. 2011 Dec 28;3(12):279-88. doi: 10.4329/wjr.v3.i12.279.
A wide spectrum of thoracic tumors have known or suspected viral etiologies. Oncogenic viruses can be classified by the type of genomic material they contain. Neoplastic conditions found to have viral etiologies include post-transplant lymphoproliferative disease, lymphoid granulomatosis, Kaposi's sarcoma, Castleman's disease, recurrent respiratory papillomatosis, lung cancer, malignant mesothelioma, leukemia and lymphomas. Viruses involved in these conditions include Epstein-Barr virus, human herpes virus 8, human papillomavirus, Simian virus 40, human immunodeficiency virus, and Human T-lymphotropic virus. Imaging findings, epidemiology and mechanism of transmission for these diseases are reviewed in detail to gain a more thorough appreciation of disease pathophysiology for the chest radiologist.
多种胸部肿瘤已明确或怀疑存在病毒病因。致癌病毒可根据其所含基因组物质的类型进行分类。已发现有病毒病因的肿瘤性疾病包括移植后淋巴细胞增生性疾病、淋巴肉芽肿病、卡波西肉瘤、卡斯尔曼病、复发性呼吸道乳头状瘤病、肺癌、恶性间皮瘤、白血病和淋巴瘤。涉及这些疾病的病毒包括爱泼斯坦-巴尔病毒、人类疱疹病毒8型、人乳头瘤病毒、猿猴病毒40、人类免疫缺陷病毒和人类嗜T淋巴细胞病毒。对这些疾病的影像学表现、流行病学及传播机制进行了详细综述,以便胸部放射科医生更全面地了解疾病的病理生理学。