Pires Ricardo A, Aroso Ivo, Silva Susana P, Mano João F, Reis Rui L
3B's Research Group - Biomaterials, Biodegradables and Biomimetics, University of Minho, AvePark, 4806-909 Taipas - Guimarães, Portugal.
Nat Prod Commun. 2011 Nov;6(11):1577-9.
Black condensates (BC) are wastes of the insulation corkboard industry that contain several valuable chemicals, including friedelin, a terpene exhibiting biological activity. Herein, we report a straightforward procedure to extract friedelin from BC. Using this procedure, we were able to extract friedelin with yields between 0.4% and 2.9% and to further purify it obtaining purities from 77.0% to 99.3% (HPLC). The initial BC (2 batches), extracted raw product and purified friedelin were analyzed using FTIR. The extraction yields and purities were found to be directly related to the intensity of the carbonyl vibration at 1713 cm(-1) in the FTIR spectrum of the used BC batch. Therefore, these spectra can be used to screen and select BC batches suitable for friedelin extraction.
黑色冷凝物（BC）是绝缘软木板工业的废料，其中含有几种有价值的化学物质，包括具有生物活性的萜类化合物木栓酮。在此，我们报告了一种从BC中提取木栓酮的简单方法。使用该方法，我们能够以0.4%至2.9%的产率提取木栓酮，并进一步纯化，获得纯度为77.0%至99.3%（高效液相色谱法）的木栓酮。使用傅里叶变换红外光谱（FTIR）对初始BC（2批）、提取的粗产品和纯化的木栓酮进行了分析。发现提取产率和纯度与所用BC批次的FTIR光谱中1713 cm(-1)处羰基振动的强度直接相关。因此，这些光谱可用于筛选和选择适合提取木栓酮的BC批次。
