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Molecular determinants of AcrB-mediated bacterial efflux implications for drug discovery.

作者信息

Manchester John I, Buurman Ed T, Bisacchi Gregory S, McLaughlin Robert E

机构信息

Department of Chemistry, Infection Innovative Medicines Unit, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States.

出版信息

J Med Chem. 2012 Mar 22;55(6):2532-7. doi: 10.1021/jm201275d. Epub 2012 Jan 27.

DOI:10.1021/jm201275d

PMID:22224562

Abstract

摘要

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Molecular determinants of AcrB-mediated bacterial efflux implications for drug discovery.

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Molecular determinants of AcrB-mediated bacterial efflux implications for drug discovery.

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